2010 Ivy Request for Proposals
The Ben and Catherine Ivy Foundation is a non-profit organization that funds Patient-Focused Research on gliomas leading to the development of better diagnostics and treatment that offer long-term survival and a high quality of life for patients with brain tumors. Since our inception in 2007, the Foundation has funded $20.2M in glioma research.
Guided by its strategic plan and mission, the Ivy Foundation is interested in funding projects on the leading edge whose primary objective is to accomplish one or more of the following in a 12-month project period starting no later than July 2010:
Enhance the output of a clinical trial for adults with GBM by performing correlative studies which significantly increase understanding of the biologic impact of a candidate therapeutic and/or interpretation of clinical response data.
Identify or validate predictors of therapeutic responsiveness by GBM molecular subtype that could potentially lead to patient stratification for therapy selection.
Determine preliminary efficacy of novel candidate therapies or validate novel therapeutic targets in GBM models.
Research proposals MUST:
Focus on one or more of the three objectives outlined above, AND
Generate definitive results that are actionable, AND
Focus on adult GBM, AND
Clearly delineate relevance of GBM model to patient tumor biology (if employing GBM model).
Successful applications will LIKELY:
Involve conducting studies in patients or in patient-derived tissue specimens.
Be collaborative, multi-institutional and/or multi-disciplinary efforts.
Have clinical outcomes data available very early on in project period if study is related to a clinical trial.
Deadline for receipt of proposals: Monday, 03/22/2010 at 12 noon (Pacific Time).
Project period: 12 months.
Total funds to be distributed: up to $1M.
Total budget per project: up to $150,000 maximum.
Scientific review process: Two-step process comprised of an Intermediate Scientific Review followed by a Final Scientific Review.
Notification to all applicants of outcome of the Intermediate Scientific Review: May 2010.
Notification of outcome of the Final Scientific Review: June 2010.
Eligibility: Only early-career researchers who received their MD and/or PhD in the last 10 years (i.e., in 2000 or after) are eligible to apply as Principal Investigator (PI) or co-PI. (Postdoctoral fellows are eligible to apply). Both the PI and co-PI must meet the eligibility requirements for early career researcher. Applicants must be affiliated with a non-profit institution or for-profit organization in the US or abroad. Joint applications between academic institution(s) and for-profit entities are accepted. There is no limit on the number of applications per PI or per institution. PIs of projects currently receiving Ivy funding are not eligible to apply as PI or co-PI.
Project start date: July 2010.
If you have any questions about the RFP, please email the Ivy Foundation at info@ivyfoundation.org. The Foundation does not set up meetings or phone calls to discuss the specifics of any research project.
For more information about the Ben and Catherine Ivy Foundation, please contact us at:
505 Hamilton Avenue, Suite 300
Palo Alto, CA 94301
Tel. 650.324.3000
Email:
info@ivyfoundation.org
