Ara Parseghian Medical Research Foundation
Request for Applications--Niemann-Pick Type C (NP-C) disease
Niemann-Pick Type C (NP-C) disease is a genetic, neurodegenerative disorder which causes progressive deterioration of the nervous system. It usually affects children by interfering with their ability to metabolize cholesterol. Adult onset may also occur. Large amounts of cholesterol accumulate within the liver, spleen, and brain. This metabolic disorder leads to a series of neurological problems that are ultimately fatal...until a treatment is found!
POTENTIAL APPLICANTS PLEASE NOTE: If you have never received funding from the APMRF, please submit electronically a Letter of Intent as outlined below. This procedure will allow our Scientific Advisory Board to read a brief summary of your proposed research without you having to submit the full grant application.Please have this letter addressed to the APMRF Scientific Advisory Board to the Foundation office by February 13, 2009. Send the Letter of Intent as an ATTACHMENT to Glen Shepherd, Executive Director: gshepherd@parseghian.orgOur SAB will review all Letters of Intent. You will be notified by April 1 whether or not the SAB would like for you to submit the full grant application for consideration of funding. The full grant applications are due no later than April 30, 2009.The Letter of Intent should not exceed 2 pages of text (12 font single spaced) and must include the following information in this order: 1. Your name, position, title, institution, address, phone and E-mail address 2. Title of proposed research study 3. The objective of the study and hypothesis to be tested 4. The relevance to Niemann-Pick Type C disease (an extensive literature review is not required) 5. Preliminary data (this is encouraged but not essential) 6. A statement of the methods to be used and a brief description of how the results will be evaluated 7. Estimated amount of award you are requesting and whether for a one- or two-year period 8. Current financial support: List each current grant or contract you have that would overlap with the conduct of this research and how this overlap will be accommodated if APMRF funding is awarded. If there are no such grants, state “NONE”If you have questions or comments on the Letter of Intent, please contact Glen Shepherd at (520) 577-5106 or gshepherd@parseghian.org
