Therapeutics Development Initiative 2009 Pre-Proposal Receipt Date: January 20, 2009 – 6:00pm US ETThe Michael J. Fox Foundation for Parkinson’s Research (MJFF) announces the launch of its Therapeutics Development Initiative (TDI) for Spring 2009, a funding mechanism to support and stimulate preclinical Parkinson’s disease research at for-profit institutions. This funding program seeks to support preclinical development of Parkinson’s disease therapies which have the potential for fundamentally altering disease course and/or improving treatment of symptoms above and beyond current standards of care. Proposals must focus on key and critical preclinical studies necessary for developing, optimizing and evaluating therapeutic strategies that if successful can move into human testing. Responsibility for the planning, direction, and execution of the proposed project will be solely that of the principal investigator who must be an employee of a for-profit entity. Academic investigators may have an advisory role in the project, but the operational and strategic ownership of the project must reside within the company. Investigators may seek up to two years of funding for preclinical development and testing of novel therapeutic approaches for the treatment or prevention of Parkinson’s disease. Please note that pre-proposals are mandatory and will be used to evaluate your proposal’s fit with the stated aims and review criteria of the RFP. All pre-proposals received in response to this program will be subjected to a triage process and only those pre-proposals deemed to be of suitable scientific merit will be invited to submit a full application. MJFF employs an expedited, abbreviated granting mechanism to accelerate discoveries and ultimately translate findings to PD patients more quickly. Conference Call MJFF will hold a 45 minute long conference call on December 16, 2008 at 12:00 PM U.S. Eastern Time to clarify and explain the Therapeutics Development Initiative 2009 program and to answer applicants' questions. To participate in this call, you must RSVP via email to conferencecalls@michaeljfox.org. Participants will receive a reply with call-in details.
While there are no restrictions as to the specific approaches to be studied under this RFP, successful applications are most likely to focus on at least one of the following categories: o Neuroprotective strategies focused on slowing or preventing the process of neuronal death. o Neuroregenerative strategies to restore or replace neuronal function. o Novel drug delivery mechanisms and/or surgical procedures. o Innovative therapeutic approaches to treat the motor and non-motor symptoms of PD, including cognitive dysfunction, autonomic dysfunction, sleep disorders, or depression among others. o Therapeutic approaches to alleviate complications of PD treatment including dyskinesias, etc.
If you would like to contact the Foundation, please call toll-free at 1-800-708-7644, or contact us by regular mail at the following address: The Michael J. Fox Foundation for Parkinson's Research Church Street Station P.O. Box 780 New York, NY 10008-0780
American Association of Diabetes Educators Request for Proposals for Building the Evidence: Problem Solving – Injections
The AADE Education and Research Foundation is offering a $40,000 grant for a research project in the field of diabetes education. The Principal Investigator must be an AADE member at the time of application; team members can be from a variety of disciplines.We are seeking proposals that address problem solving issues and potential solutions surrounding effective insulin/medication injection in patients with a BMI>35 or very low body fat. The overall aim is to identify best practices and effective problem solving solutions for populations who have difficulty with administration of their injections.Proposals must be postmarked by the first business day of November (Monday, November 3, 2008)
Specific AimsCurrently, there is a lack of research on problem solving issues and potential solutions surroundingeffective insulin/medication injection in patients with a BMI>35 or very low body fat. The overall aim is toidentify best practices and effective problem solving solutions for populations who have difficulty withadministration of their injections. The proposed research must examine the problems that individuals atboth the high and low ends of the BMI Index face regarding injection of insulin or other diabetesmedication with a syringe or insulin pen. The findings will be sufficiently robust that they can bedisseminated to diabetes educators via a presentation and/or publication.The Researcher will describe in detail the problem solving and injection intervention(s) that will be used,which method of data collection and analysis will be appropriate for the study, suggested methods fordata collection and analysis follow. The proposed study should also address potential issues, such asinability of patient to see the injection site due to excess abdominal fat and inability to locate anappropriate injection site due to low body fat. Once the problems have been identified and documented,the researchers should implement and evaluate one or more problem solving interventions.Research questions1. What are the knowledge, skills and problem solving behaviors that people with diabetes need toeffectively self-manage their injections?2. What injection techniques should health care professionals use to educate patients to insure that eitherobese (BMI >35), extremely thin (BMI <18.5 or extremely muscular) effectively inject insulin or otherdiabetes medications once they leave the clinical setting?3. What problem solving questions or activities can the CDE employ to ensure that the proper techniqueis used and/or adjustments to technique are made for the target populations?This proposal must address these research questions, specific research aims, and state theintended objectives of the proposed study. Applicants must state the rationale for theirapproach to the problem and state the hypothesis this research is designed to address.SignificanceBriefly describe the background information relevant to this proposal, including a brief evaluationof the existing body of knowledge about the problem. Identify the importance of this study to thefield of diabetes education and/or diabetes nursing practice.
http://www.diabeteseducator.org/Foundation/Grants/CurrentGrants.html
ADA-ASP Young Investigator Innovation Award in Geriatric EndocrinologyAward Description: The American Diabetes Association (ADA)-Association of Subspecialty Professors (ASP) Young Investigator Innovation Award in Geriatric Endocrinology provides grant support to new investigators. This program supports entry-level faculty to integrate geriatrics with novel basic, clinical, or health services diabetes research. This award supports pilot and feasibility studies that may lack preliminary data, but offer considerable promise for the cure, prevention, or treatment of diabetes in an aging population.Support: Awards are a maximum of $75,000 per year for up to two years. No indirect costs may be requested.Deadline Dates: July 15, 2008 for January 1, 2009 funding and January 15, 2009 for July 1, 2009 funding.
Call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383). Our hours of operation are Monday - Friday, 8:30 AM - 8 PM Eastern Standard Time.Or write to us:American Diabetes AssociationATTN: National Call Center1701 North Beauregard StreetAlexandria, VA 22311
American Diabetes Association-Takeda Beta Cell in Diabetes Postdoctoral Fellowship AwardAward Description: These awards, funded by Takeda Pharmaceuticals North America, Inc., are granted to established diabetes investigators to support the training of scientists in an environment most conducive to beginning a career in diabetes research and beta cell biology.Support: Awards are $45,000 a year for up to two years. No indirect costs may be requested.Deadline Dates: January 15, 2009 for July 1, 2009 funding. Please note: Funding is not available for this award in 2008.
American Diabetes Association-Takeda Pharmaceuticals Cardiovascular Complications in Diabetes Postdoctoral Fellowship AwardAward Description: These awards, funded by Takeda Pharmaceuticals North America, Inc., are granted to established diabetes investigators to support a postdoctoral fellow being trained in the area of diabetes and cardiovascular disease.Support: Awards are $45,000 a year for up to two years. No indirect costs may be requested.Deadline Dates: January 15, 2009 for July 1, 2009 funding. Please note: January funding is not currently for this award.
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