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Howard Hughes Medical Institute Medical Research Fellows Program
Application Deadline: January 11, 2014 2 p.m. ET
The Medical Research Fellows Program gives students the opportunity to immerse themselves in a year of basic, translational, or applied biomedical research. Medical Fellows experience the excitement and intellectual rewards of research before making plans for residency or postgraduate training. The students select their own mentor at any academic or nonprofit research institution in the United States (excluding the National Institutes of Health) or abroad, provided the proposed mentor is affiliated with a U.S. fellowship institution, and work with the mentor to develop a research proposal. Mentor selection and the research project proposal are key components of the application. Working with an HHMI investigator, early career scientist, or HHMI professor is encouraged but not required.
Medical Fellows conducting research in the following areas may be supported by organizations partnering with HHMI:
Epilepsy research (Partner: Citizens United for Research in Epilepsy);
Inherited retinal degenerative disease research (Partner: Foundation Fighting Blindness);
Duchenne muscular dystrophy research (Partner: Duchenne Research Fund);
Parkinson's disease research (Partner: Parkinson's Disease Foundation);
Preclinical research in interventional radiology (Partner: Society of Interventional Radiology Foundation); and
Veterinary student research (Partner: Burroughs Wellcome Fund).
HHMI Medical Fellows will:
focus on research without the distraction of full-time coursework;
become part of a community of Medical Fellows through regional meetings and other events;
gain insight into a wide range of research areas and receive career advice from program alumni and other prominent physician-scientists;
interact with HHMI investigators at an HHMI science meeting and learn about their latest findings;
share their research and network with other trainees and renowned biomedical investigators at two Medical Fellows conferences during the year;
participate in scientific conferences in their field and present your their work;
spend a year evaluating whether research should be part of their career.
Students must be in good standing at a medical, dental, or veterinary school located in the United States.
U.S. citizenship is not required, but students must be eligible to work with an appropriate visa.
Students cannot be enrolled in a combined medical, dental, or veterinary/PhD program (e.g., MD/PhD) or PhD, or ScD program, or have a PhD or ScD in a laboratory-based biological science.
Parkinson’s Disease Foundation-Parkinson Study Group Mentored Clinical Research Award
The Mentored Clinical Research Award (MCRA) for new investigators is funded by a grant from the Parkinson’s Disease Foundation (PDF) to the Parkinson Study Group (PSG). The grant supports new investigators for a one-year project in patient-oriented research in Parkinson’s disease or other parkinsonian disorders under the mentorship of an experienced investigator. The goal of the award is to provide funding for an investigator who has the potential to become an independent researcher.
It is anticipated for the current application period that an award of $50,000 will be available. Only direct costs will be funded by this award.
Eligibility & Restrictions
Applicants for the MCRA should be clinicians and scientists who are within five years of having completed formal training. Fellows may apply. If during formal training unusual circumstances occurred to delay completion, “time out” periods will be permitted and should be explained in the application cover letter.
Applicants must identify an appropriate mentor or mentors with extensive research experience. Either the applicant or the mentor must be a member of the PSG. An applicant may have co-mentors.
Proposals for the MCRA are due on Friday, January 3, 2014, to be considered for funding. Please note that this is a collaborative fellowship and for this program, applicants cannot use PDF's online grant management system. Instead, applicants should submit an electronic copy of the proposal in Microsoft Word of .pdf format to the PSG to Roseanna.Battista@ctcc.rochester.edu with a cover note that includes the candidate’s name and the title of proposal.
Proposals should be hypothesis driven and amenable to completion in a one year time period. The proposal should be directed toward patient oriented research in Parkinson’s disease or related parkinsonian disorders.
All applications for this fellowship should include the following elements:
The focus of the proposal must relate to an area of importance in the field. The research plan should address unmet needs of people living with PD, have the potential for broad application among the PD community, and lead to advances in clinically relevant treatment options;
A research proposal (five pages in length) including an abstract, specific aims, background and significance, preliminary studies and experimental designs and methods;
A clear description of the educational plan that will be implemented to educate the candidate in development of appropriate research methodology under the direction of the mentor;
A statement of the qualification of the mentor(s) to guide the research program.
An electronic copy of the proposal in Microsoft Word or pdf-format;
The candidate’s proposal should be formatted according to the guidelines indicated on the PSG website.
The research plan itself should not exceed five pages. The candidate should also include a four-page NIH-style biosketch and other support statement for both the applicant and the mentor(s);
The proposal should include a statement from the mentor(s) including information on research qualifications.
The statement should include the nature of the supervision that will occur during the award period and an agreement to provide mentorship to the candidate for the award period. The mentor must include information on what skills they plan to teach the mentee and how previous fellows they mentored are contributing to Parkinson’s research (if applicable);
A budget and brief budget justification are required for all funds requested. No indirect costs will be funded;
The funding request should not exceed $50,000;
Clinical research proposals need not be pre-approved by institutional IRB, but should include a Human Studies section that addresses concerns pertaining to risk, benefit and consent (not included in the five page limit);
Revised applications should include an Introduction of not more than one page that describes how the applicant has responded to the reviewers’ criticisms.
Review & Decisions
Proposals received within the specified time frame are reviewed by the PSG Mentoring Committee. Applicants will be notified of the results on Monday, March 3, 2014. Funding will begin on July 1 and continue until June 30.
Successful applicants will be required to submit a short written summary of progress at six months and at one year after funding and attend the annual PSG meeting to present the results of the research done during their fellowship year. The meeting expense will be supported by the PSG separately from the grant award.
Parkinson's Disease Foundation Summer Student Fellowships
Applications due: Monday, January 27, 2014
PDF’s Summer Fellowship Program is used to support students – from advanced undergraduates to graduate and medical students – in their pursuit of Parkinson's-related summer research projects. The goal of the Summer Fellowship is to cultivate an early interest in Fellows into the cause and possible treatments for Parkinson's disease.
Fellows work under the close supervision of a sponsor who is an expert in the Parkinson's community and oversees the project. Typically, summer fellowships are offered for 10 weeks of clinical or laboratory work with an award of $4,000.
The award is to be used to support the student's summer research, for example, to defray tuition costs of research credits or to supplement living/housing costs. This award may taxable; an IRS form 1099 will be sent to the recipient at the end of the calendar year.
Undergraduate students, graduate students and medical students are all eligible for summer fellowships. Each applicant must identify a mentor with whom he or she will conduct the proposed project. This program is open to both national and international applicants.
Please note that this year, all applications must be submitted online through the PDF website at grants.pdf.org; no paper copies will be accepted. This application period typically opens in December closes at the end of January. Successful applicants are typically notified in mid-April of PDF's decisions.
Briefly, a complete application will consist of the following five items:
Brief, two-page proposal describing the research plan (written by applicant in conjunction with mentor);
Copy of the student’s academic transcript (unofficial is acceptable);
Statement by the applicant, describing why he or she is interested in conducting Parkinson's research, his or her qualifications, and the relevance of this research to his or her career/research interests;
Letter of support, written by the mentor under whom the applicant plans to work, discussing qualifications of the student, affirming that facilities and materials will be available and agreeing to actively guide the student’s work. This letter must be sent separately by the mentor either via email to firstname.lastname@example.org with “SUMMER FELLOWSHIP” in the subject line or via regular mail to Parkinson’s Disease Foundation; Summer Fellowship Letter of Support; Attn: Dr. Beth Vernaleo, Grants Manager; 1359 Broadway, Suite 1509, New York, NY 10018.
All letters must be received by the application deadline.;
Application form, completed.
Note: Incorrect or incomplete applications will be rejected without comment.
Applications are judged based on the feasibility of the applicant's project, the background of the applicant and the appropriateness of the mentor. Final decisions are typically made in mid-April. PDF will contact all candidates at that time. Funding for successful applicants may commence as early as June 1.
Parkinson Study Group Mentored Clinical Research Award for New Investigators in Patient-Oriented Research in Parkinson’s Disease and Related Disorders
The Mentored Clinical Research Award (MCRA) for new investigators is funded by a grant from the Parkinson’s Disease Foundation (PDF) to the Parkinson Study Group (PSG). The purpose of this grant is to support a new investigator for a 1 year project in patient oriented research in Parkinsons disease or other parkinsonian disorders under the mentorship of an experienced investigator. The goal of the Award is to provide funding for an investigator with the potential to become an independent researcher. Appropriate applicants for the MCRA are clinicians and scientists who are within 5 years of having completed formal training. The applicant must identify an appropriate mentor or mentors with extensive research experience. Either the applicant or the mentor must be a member of the PSG.
Application deadline: Friday, January 3, 2014
Award available: $50,000
Notification of award: March 3, 2014
Michael J. Fox Foundation for Parkinson's Research Target Validation Program
Fall 2014 Review Cycle
Informational Conference Call*: March 26, 2014 at 12pm US ET
Pre-proposals Due: May 28, 2014 – 6pm US ET
Full Proposal Invitations: June 18, 2014
Full Proposals Due (by invite only): August 6, 2014 – 6pm US ET
Anticipated Award Announcement: October 2014
Anticipated Funding: November 2014
*MJFF will hold a 45-minute conference call on the dates and times listed above to clarify and explain the goals of this funding initiative and answer applicant questions. To participate in the call and receive call-in details, please RSVP via email to email@example.com.
The Target Validation program supports work to determine whether manipulation of a defined biological target provides a disease-relevant beneficial outcome in a whole animal, mammalian model of PD. MJFF does not have any pre-conceived preferences for particular targets submitted to the Target Validation program. However, we recommend applicants consider the following:
The target should be clearly defined, such as:
A specific gene
A structural/functional feature of a protein (e.g., its enzymatic activity, protein conformation or ability to interact with other proteins)
Proposals seeking to manipulate global pathways without a clear target are not encouraged
Applicants may propose a variety of methods to manipulate a target, including but not limited to:
Use of pharmacological tools
Supporting data/explanation of the proposed pharmacological tool must be addressed in the body of the proposal.
Parameters that should be discussed include:
Selectivity for the target of interest
Pharmacokinetic/Pharmacodynamic measures that have been/will be assessed
Measures of target engagement
Use of biologic strategies such as:
Viral vector-mediated gene delivery, etc.
In Vivo Models
Applicants may also propose use of models appropriate for the target proposed including:
Previously established genetically engineered animal models including:
Knockout models where the target/gene of interest is deleted
Transgenic models whereby the target/gene of interest is over-expressed
Investigators should proposed to examine PD-relevant features or sensitivity to PD-associated factors during the course of their studies
Proposals may include intermediate tests using in vitro, ex vivo and/or model organisms (e.g., Drosophila, C. elegans) to optimize the ideal target manipulation strategy
These proposals must ultimately include within the grant funding period an evaluation of the target manipulation in a whole-animal mammalian model of PD
Note: The following types of proposals are not appropriate for the Target Validation program:
Proposals focused on new target identification and proposals testing cellular transplantation approaches.
Proposals seeking to generate new genetic (knockin, knockout, transgenic) models
Investigators seeking guidance to develop new models around their target are encouraged to contact firstname.lastname@example.org
Applicants seeking support for therapeutic development should submit to the Therapeutic Pipeline Program or contact MJFF research staff for guidance.
MJFF will commit up to $10 million to the Edmond J. Safra Core Programs for PD Research with the intention to support multiple awards. The Target Validation program supports two-year grants up to $250,000 total costs inclusive of both direct and indirect costs. The total annual direct costs cannot exceed $100,000. No more than 25% (Academic institutions) or 10% (for-profit organizations) of the direct costs may go to indirect costs.
Applications may be submitted by:
U.S. and non-U.S. biotechnology/pharmaceutical companies or other for-profit entities, either publicly or privately held,
U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.
Post-doctoral fellows are NOT eligible to apply as Principal Investigators to the Target Validation program.
Walter G. McMillen Memorial Award for Parkinson’s Disease Research
The Walter G. McMillen Memorial award is designed to encourage graduate student’s interest in research on Parkinson’s disease.
Potential research topics that will be funded by this award include, but are not limited to:
The assessment and treatment of persons with Parkinson’s disease.
The impact of this diagnosis on family support systems (e.g., caregiver burden).
For the purposes of this award, the term "research" is broadly defined to include any scholarly endeavor, including but not limited to experiments, correlational studies, qualitative investigations, historical work, case studies, and evaluation research.
However, the focus of this research must be on the assessment, treatment, or management of Parkinson’s disease.
The cash award of $1,000 is intended to offset direct costs associated with the planned research. These may include salaries, equipment, supplies, stipends for study participants, etc.
Note that the monies will be awarded to the candidate’s institution and not directly to the applicant.
Indirect costs are not supported by this award. Candidates should contact their grants office to ensure that indirect costs can be waived prior to applying for this award.
Annual deadline: March 15
The award competition is open to doctoral-level graduate students.
Only one submission per student will be reviewed each year.
The funded research proposal is expected to be conducted during the next academic year.
To be eligible for this award, the student must initiate and conduct the project under the supervision of a professor or research advisor. The applicant is expected to be the principal investigator on the project.
How to Apply
Research proposals should include:
An abstract (up to 400 words)
A research plan (not to exceed five pages using 12-point font or larger), including:
• Specific aims/hypotheses
• Background and significance
• Research design and methods
• How the grant funds will be used
• Cited literature
Applicants must also submit:
A biographical sketch (not to exceed one page), that includes in list format:
• Schools attended with degrees attained
• Relevant professional position
• Society memberships
• Publications and/or paper presentations
• Relevant coursework
• Any other relevant information you would like to include
A short supporting statement by the faculty sponsor verifying the nature of and the relative contribution to the research by the student submitting the proposal. This statement should be short, not to exceed one paragraph, and emailed directly from the advisor.
Please submit applications electronically as an email attachment to the co-chair of the Awards Committee. Type "McMillen Award Submission" in the subject line of the email.