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Call for Applications: Clinical Trials in Thalassemia Cell and Gene Therapy Grant Award
The purpose of this initiative is to speed the application of recent translational advances in gene therapy to clinical trials. The Foundation recognizes that there are many key areas worthy of support in the search for a cure for thalassemia with cell therapy and gene therapy. While several funding mechanisms are available for a range of studies on vector development, proof of concept studies in animal models, and transplantation, there remains a funding gap for launching human trials. Both phase I (safety) and phase II (efficacy) trials are eligible for support. Funding and candidate eligibility: Total funding of up to $60,000 per year will be available (including indirect costs of 8%). With satisfactory evidence of progress the grant may be renewed for a second year. The research may not be conducted at a for-profit laboratory. Because the purpose of the support is to facilitate launch of clinical trials, eligible studies proposed for this RFA must be accompanied by a realistic timeline of progress to human trials. The Foundation recognizes that this timeline can be long. Applicants should state explicitly the status of their proposed trials, for example whether the trial has been approved by the recombinant DNA Advisory Committee (RAC), or Food and Drug Administration (or equivalent processes at non-US sites), or whether review meetings at regulatory agencies have been scheduled. Awards will be announced in June 2014.
The completed application is due Monday February 3, 2014.
Endoscopic Research Awards
Submission Deadline: January 31, 2014 at 5pm CST.
ASGE Endoscopic Research Awards are offered to physicians for projects in basic, translational and clinical endoscopic research. The ASGE is particularly interested in endoscopic research pertaining to colorectal cancer, Barrett's esophagus, endoscopy training/credentialing/simulation, endoscopic issues specific to under-represented minorities (defined as women and individuals of diverse ethnic/cultural backgrounds), measuring/improving quality and efficiency in endoscopy, endoscope reprocessing and infection control (especially vacuum canisters), endoscopy/anesthesia monitoring and preparation (especially CO2 monitoring), comparative effectiveness with competing technologies/therapies, NOTES, novel endoscopic treatments for obesity, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography (ERCP), and other endoscopically-guided imaging/intervention. The research committee will consider funding "seed" projects if there is an explicit outline for subsequent projects, and their funding plan (e.g. NIH, VA Merit), based on the preliminary data generated by the proposed pilot.
To foster research in routine and advanced gastrointestinal endoscopy.
Candidate must be an ASGE member (ASGE membership at the time of application is a requirement for eligibility for grants and awards), be an MD (or have equivalent degree), and be currently practicing in a gastrointestinal endoscopy-related academic institution or private practice setting in North America (international applications will be considered as described below). Candidates who are delinquent on prior ASGE research grant progress reports are not eligible for future ASGE funding. If the candidate is a trainee, there must be a letter from the Division Chief confirming the trainee's ongoing appointment at the institution for the duration of the grant, and their position title, and/or a contingency plan.
Grants may be requested for up to $75,000 in total funding, and spread over two years of study. Note: If the application is not selected for the Quality in Endoscopy Research Award, it will still be considered for an Endoscopic Research Award.
Requests for funding "seed" projects that will lead to further research, as well as larger requests for definitive clinical trials will be considered. In order to maximize the funds available for research, money for travel to meetings will not be provided, nor will funding be provided for indirect costs.
Grants are awarded based on the scientific merit of the proposal and assessment of the investigator's ability to complete the project (supportive environment, experience, training, availability of patients and other resources needed). The proposed research project must be approved by the ASGE Research Committee and should also be of such quality as to lead to presentation at Digestive Disease Week® and subsequent full publication. One objective of these ASGE awards is the eventual submission of larger research funding requests, including federal funding, and proposals with such potential will be given priority.
ASGE International Members are eligible to apply for an Endoscopic Research Award (Current ASGE membership is a requirement of eligibility for grants and awards). The ASGE Research Committee will consider funding one international project for up to $75,000. The project justification should explain the relevance of the project to the ASGE membership, and should explain if there are unique reasons why an international location for the project might be more feasible than in North America. All other standards listed above will apply to international applicants. Please contact firstname.lastname@example.org or Liz O'Keefe at 630.570.5623 for more information on eligibility.
National Blood Foundation Scientific Research Grants Program
All applications must be received at the NBF office by 11:59 pm ET, December 31, 2013. Extensions will not be granted.
Funds are raised annually from corporations, blood centers, foundations and individuals by the NBF for the National Blood Foundation Research and Education Trust Fund (NBFRET) and the NBF. The NBF and NBFRET, which are 501(c)(3) organizations, provide grants for scientific research in the field of transfusion medicine and cellular therapies and support educational initiatives that benefit this community. Since 1985, the NBF has distributed approximately $8 million to 182 early-career scientists. The National Blood Foundation annually awards grants for one or two-year research projects, with a maximum award per grant of $75,000.
NBF is pleased to announce the availability of funding in 2014 for scientific research projects related to transfusion medicine and cellular therapies. NBF will award grants for investigator-initiated original research in all aspects of blood banking, transfusion medicine and cellular therapies. NEW in 2014, patient blood management is introduced as a research content area.
Important areas of research for the grant program include:
Alloimmunization, immune modulation, and tolerance
Animal models for the study of graft-vs-host disease
Biology of autoimmune hemolytic anemia
Autologous and allogeneic stem cell transplants
Detection of residual disease following stem cell transplants
Effects of growth factors in vitro and in vivo
Biochemistry of coagulation factors
Blood group serology
Biochemistry of red cell antigens
Molecular genetics of the blood groups
Studies on Lyme disease, West Nile Virus, SARS and babesiosis and other emerging diseases
Effect of allogeneic transfusion in HIV-infected and immunocompromised patients
Improved detection of transfusion - transmitted diseases
Cell separation, cell culture or expansion studies for cell therapy applications
Development of novel cell therapies or assays to measure cell viability or function
Pilot studies in regenerative medicine
Studies on mechanisms or roles of cells in stem cell transplantation
Studies on cytokines or growth factors involved in stem cell differentiation
NEW!! PATIENT BLOOD MANAGEMENT
Treatment of pre-admission anemia and bleeding tendencies; Intraoperative/postoperative blood recovery; Surgical hemostasis; Appropriate indications for transfusion; Changing physician behaviors; Blood utilization review.
Grants applications are evaluated on the basis of their scientific merit, relevance to and impact on transfusion medicine, focus and appropriateness to the scope of funding, and likelihood of yielding meaningful data.
An applicant must be a doctor (MD or PhD), medical technologist, transfusion medicine or cellular therapies professional. All applicants will be considered regardless of age, race, gender, national origin or religion.
The NBF accepts national and international applicants who are ideally no more than five years post-doctoral training.
Applications for research into innovative and new projects are a priority.
Emphasis is given to applicants who have not previously received an NBF grant.
No candidate is eligible to receive more than two NBF grants for separate projects.
No particular project can be funded more than once.
An application for the same project may be submitted up to three times if not already NBF funded.
Awards will not be made to increase the funding available for currently funded research projects. NBF grants are intended to provide "seed" funding that allows the principal investigator to enhance preliminary data. This data may then be useful in applying for larger grants.
All applicants will be charged an application fee of $150 except for principal investigators who are individual members of the AABB. AABB institutional membership does not qualify. To become an AABB member, please contact AABB's Membership Services at +1.301.215.6489 or email@example.com.
Contact NBF at +1.301.215.6552 or firstname.lastname@example.org.
Shwachman-Diamond Syndrome Foundation Grants
Shwachman-Diamond Syndrome (SDS) is a multi-system autosomal-recessive disorder characterized by exocrine pancreatic dysfunction, and varying degrees of marrow dysfunction with cytopenias. Many associated clinical problems have also been described, including skeletal anomalies, metaphyseal dysostosis, rib abnormalities, cleft palate, dental abnormalities and others. Shwachman-Diamond Syndrome Foundation (SDSF) is a nonprofit support organization actively helping the victims of this disease. SDSF is accepting grant requests for research relevant to this disease. Any high quality, innovative research proposal deemed relevant to SDS will be considered. The following are areas of particular interest:
Investigate or evaluate potential novel therapies or potential novel therapeutic strategies- preferred applications
Evaluate predictors of bone marrow abnormalities to determine their correlation with the disease
Determine the causes of and investiagte treatments for bone marrow failure and leukemia
Evaluate protocols and regimens for bone marrow transplants
Evaluate causes and investigate treatments for graft vs host disease and other infections of post bone marrow transplants
Investigations related to adult patient presentation, management, and care including transition from pediatric-centered to adult care
Persons applying for these grants must be in a faculty position with authority to hold an independent research grant (not a training position).
Letter of Intent
The potential applicant should write a one-page letter of intent to the SDSF, indicating the applicant’s position and affiliation, describing their planned project, and explaining its relevance to Shwachman-Diamond Syndrome. These letters are reviewed by SDSF’s Medical and Scientific Advisory Board (MSAB) grant review process.
This letter will be used to identify applicants who will be asked to provide a full application.
The letter is due no later than March 12th. All those who have submitted a letter of intent will receive a reply by April 5th. All Grant Applications must be submitted by May 15th. The final grant decision will be announced by July 31st with a November 1st start date.
Terms of Support
Support may be provided for up to two (2) years in an amount not to exceed $35,000 per year, including expenses. The second year funding will not be released until a Progress Report has been reviewed and approved by the MSAB. The date for the Progress Report is October 1st. Applicants may submit only one grant application at a time, and may hold only one grant at a time.
If you would like us to send you a grant application, have any questions regarding the grant process or have an interest in the disease, please contact SDSF at the address indicated on the home page of our website, call toll free 1-888-825-SDSF (7373) or via email at email@example.com.
Broad Medical Research Program Inflammatory Bowel Disease Grants
Recognizing that some of the most promising research in this area of medicine is at the very early stages of development, the Broad Medical Research Program funds studies and investigation of new ideas in their initial exploratory stage that do not yet qualify for funding from more traditional sources like the National Institutes of Health. By supporting innovative and promising ideas, we hope to advance the research so it is likely to receive continuation funding from other sources. The Broad Medical Research Program awards one- and two-year grants for basic or clinical IBD research projects to qualified investigators from around the world who work in a nonprofit academic organization. Grant applications submitted to the Broad Medical Research Program are not reviewed by a committee. Instead, leading investigators in each research area review proposals and provide suggestions for improvement. Over 1,900 reviewers from 41 countries have participated in the review process. Proposals are selected for funding based on their scientific strength, innovation and relevance to IBD diagnosis, therapy or prevention. To expedite the research, we accept applications year-round and fund approved applications in about three months.Because we believe that great ideas could come from non-traditional sources, we encourage basic and clinical investigators and scientists not currently working in IBD and interdisciplinary teams to apply.Application ProcessThere is a two-step process for requesting funds from the Broad Medical Research Program:1. The first step is to submit a Letter of Interest. Decisions on Letters of Interest are based on external expert review of the proposal and usually are made within four to six weeks. Instructions for Letters of Interest can be found at www.broadmedical.org.2. If we are interested in pursuing a project, an invitation is extended to submit a full grant application. At that time, the grant application instructions and forms are sent to the Principal Investigator. Decisions on grant applications are made based on external review by subject experts and usually take eight to 10 weeks.There are no deadlines or specific dates for applications. Proposals are accepted and reviewed year-round.Proposal Review• Most Letters of Interest and all grant applications will be evaluated by active investigators in the specific research area.• Reviewers are located throughout the world and are chosen carefully not to have conflicts of interest with the applicants.• Grant proposals will be selected for funding based on their scientific strength, innovative value and relevance to IBD diagnosis, therapy or prevention.• Decisions on Letters of Interest will usually be made within 4-6 weeks.• Decisions on grant applications will usually be made within 8-10 weeks.Funding Guidelines• Preference is given to proposals with strong potential of clinical benefit to IBD patients in the foreseeable future.• Funding can be requested for up to two years.• Funding of a second year will be based on an evaluation of the progress and the perceived value of the findings from the first year of funding.
Letter of Interest Submission 1. Direct Letters of Interest to: Daniel Hollander, M.D. Director Broad Medical Research Program The Eli and Edythe Broad Foundation, Scientific | Medical Research 10900 Wilshire Boulevard, Twelfth Floor Los Angeles, California 90024-6532 U.S.A. 2. If possible, please send your Letter of Interest and all attachments electronically to: firstname.lastname@example.org. If you send it electronically, please do not send a printed copy. 3. Receipt of your Letter of Interest will be acknowledged by e-mail within a few days. If you do not hear from us in a timely manner, please contact us at email@example.com to make sure that your letter has been received. 4. You may include suggestions for potential reviewers and also indicate individuals with potential conflicts of interest. Unless required by your institution, Letters of Interest may be submitted directly to the BMRP by the Principal Investigator and do not require institutional approval or signature. 5. Letters of Interest are accepted and reviewed throughout the year; there are no deadlines.