Grants>Motor Neuron Diseases

Request for Proposals: Funding Opportunities for Kennedy’s Disease Research

The Kennedy’s Disease Association (KDA) is planning to fund one or more research grants this fall to further the understanding of the pathological mechanisms of Kennedy’s Disease.

The KDA projects that funding for each grant will be up to $25,000.

Applications from junior investigators and from senior post-doctoral fellows are encouraged.

Your proposals must be received by Friday, June 21, 2013.

ALS Therapy Alliance Grants Program

Thank you for your interest in submitting a proposal for grant funding to the ALS Therapy Alliance (ATA). Our organization traditionally awards grants from one to three years in term ranging from $100,000 to $1 million in funding to both non- and for-profit companies. National and international companies are eligible to apply.

The following outline will help you prepare the information needed for our next funding review, which happens twice a year in April and November.

Please note grant submission deadlines and number of copies requested in order to ensure timely processing of your application. The ALS Therapy Alliance does not cover indirect costs.

If you have questions about the submission process or this application, please contact Ray Bisson, Grants Manager at (603) 664-5005 or ray@alstherapyalliance.org, or visit our FAQ page.

http://alstherapyalliance.org/index.php/research/grant-submission-process/faqs.html

What to include with your grant proposal

ATA grant applications should follow the following format and adhere strictly to the maximum page limits (using only 11 point font or greater):

■ Abstract (1 page)

■ Background and Significance (2 pages)

■ Preliminary Data (2 pages)

■ Experimental Plan (3 pages)

■ References (no limit)

■ Budget

■ Budget Justification

■ NIH Biosketch (including present and pending support, 4 pages maximum) for PI's, post-docs and others involved in the project (excluding laboratory technicians)

■ Letters of collaboration and support

Grant proposal submission deadlines

To have your grant proposal reviewed at our April meeting, please submit by March 15th. To have your grant proposal reviewed at our November meeting, please submit by October 15th.

Where to send your grant proposal

Please email your proposal in PDF format to ray@alstherapyalliance.org.

ALS Therapy Alliance Grants Program

Thank you for your interest in submitting a proposal for grant funding to the ALS Therapy Alliance (ATA). Our organization traditionally awards grants from one to three years in term ranging from $100,000 to $1 million in funding to both non- and for-profit companies. National and international companies are eligible to apply.

The following outline will help you prepare the information needed for our next funding review, which happens twice a year in April and November.

Please note grant submission deadlines and number of copies requested in order to ensure timely processing of your application. The ALS Therapy Alliance does not cover indirect costs.

If you have questions about the submission process or this application, please contact Ray Bisson, Grants Manager at (603) 664-5005 or ray@alstherapyalliance.org, or visit our FAQ page.

http://alstherapyalliance.org/index.php/research/grant-submission-process/faqs.html

What to include with your grant proposal

ATA grant applications should follow the following format and adhere strictly to the maximum page limits (using only 11 point font or greater):

■ Abstract (1 page)

■ Background and Significance (2 pages)

■ Preliminary Data (2 pages)

■ Experimental Plan (3 pages)

■ References (no limit)

■ Budget

■ Budget Justification

■ NIH Biosketch (including present and pending support, 4 pages maximum) for PI's, post-docs and others involved in the project (excluding laboratory technicians)

■ Letters of collaboration and support

Grant proposal submission deadlines

To have your grant proposal reviewed at our April meeting, please submit by March 15th. To have your grant proposal reviewed at our November meeting, please submit by October 15th.

Where to send your grant proposal

Please email your proposal in PDF format to ray@alstherapyalliance.org.

Request for Proposals: Phase II Clinical Development of Novel, High-Potential Treatments for People with ALS

Letter of intent due: May 20, 2013

Submit letter of intent to researchgrants@alsa-national.org

The Massachusetts General Hospital Neurological Clinical Research Institute (NCRI) and The ALS Association are pleased to announce a call for phase II clinical trial applications for novel, high-potential treatments in Amyotrophic Lateral Sclerosis. The call for clinical study proposals is intended for academic-industry partnerships, including pharmaceutical, biotherapeutic/biotechnology companies, academic members of the Northeast ALS Consortium (NEALS), and ALS scientists throughout the world. A total of USD $800,000 (direct costs only) in NCRI/ALS Association clinical research support is available.

Potential Phase II clinical trials should include interventions that have:

A. a pharmacodynamics marker that can measure whether pathway of interest has been affected, and

B. a plan to collect samples for biomarker studies.

Applications will be reviewed by a joint NCRI and ALS Association steering committee and will be judged on:

-- Scientific rationale and merit, novelty, and the value of the project.

-- Availability of appropriate facilities and the technical ability to carry out the clinical study.

Funds will be awarded in the form of infrastucure support provided by NEALS and its Coordination Center, the NCRI, and funds for per subject fee, sample collection, pharmacodynamic marker testing and other trial related costs as needed. Applicants may apply for a combination of any of the following clinical research support services available through NEALS and the NCRI:

-- Project Management

-- Grants & Contracts Management

-- Data Management

-- Study Monitoring

-- Outcome Measure Development and Training

-- Biostatistical Support

-- Site Selection, Start Up, Regulatory Document Review, and Ongoing Site Management

-- Site Trainings: Good Clinical Practice, Regulatory Compliance, and Site Management

The successful applicant will retain control of the trial as well as intellectual property relating to the therapeutic agent being investigated. The NCRI and The ALS Association are extremely well-positioned to work with both academic and industry partners to rapidly bring the best ALS science into clinical testing. Since infrastructure support is provided by this grant, applicants are required to contact NEALS/ALS Association prior to their grant submission to collaborate on the budget portion. Applicants may request the full $800,000 in NCRI/ALS Association research support or may request a smaller amount, depending on the appropriate needs of the proposed study.

Deadlines:

Letter of Intent: May 20, 2013

Notification to submit full application June 20, 2013

Full Application: August 15, 2013

Recipients Announced: October 2013

Award Starts: November 2013

Reeve Foundation Quality of Life Grants Program

The Reeve Foundation Quality of Life Grants Program awards grants to nonprofit organizations that provide services to individuals with paralysis.

Quality of Life grants, conceived by the late Dana Reeve, are awarded to programs or projects that improve the daily lives of people with paralysis, with some emphasis on but not limited to paralysis caused by spinal caused by spinal cord injuries. She started the Quality of Life grants program to recognize and support organizations that recognize and support organizations that help disabled individuals, their families and caregivers in ways that more immediately give them increased independence, day-to-day happiness, and improved access.

Funding is awarded twice yearly to nonprofit organizations that provide critical life-enhancing and life-changing programs and services that improve physical and emotional health. Funded projects offer a diversity of services and approaches: improving access; providing education and job training; sponsoring organized sporting opportunities; and more to individuals living with paralysis and their communities.

Quality of Life grants are funded through a cooperative agreement with the Centers for Disease Control and Prevention (Award #1U59DD000338-1).These grants are awarded to nonprofit organizations that address that needs of people living with paralysis caused by spinal cord and other injuries, diseases and birth conditions, including (but not limited to) stroke, spina bifida, multiple sclerosis, cerebral palsy and amyotrophic lateral sclerosis (ALS).

The Reeve Foundation gives special consideration to organizations that serve returning wounded military and their families, and to those that provide targeted services to diverse cultural communities.

Since 1999, the Reeve Foundation has provide 2,055 grants totalling over $15.7 million to organizations worldwide that help improve opportunities, access and quality of life for individuals living with paralysis, their families and their communities. This program recognizes the unique and numerous needs of these individuals and the importance of providing services and programs that enable them to participate in all areas of life.

Who Should Apply?

The Reeve Foundation supports, through Quality of Life grants, nonprofit organizations that serve individuals with physical disabilities, particularly paralysis, and their families. The Foundation aids larger organizations in representing and protecting the individuals with physical disabilities on a national level as well as local groups in having an immediate and practical impact on individual lives.

Quality of Life grants are most often awarded to nonprofit organizations that have IRS 501(c)(3) status, but may also be awarded to community parks, schools, veterans hospitals, tribal entities, etc. Most Quality of Life grants are awarded within the United States of America, although the Reeve Foundation does award a small number of grants to nonprofit organizations based outside the United States.

2013 Program Timeline

• 1st Cycle online application submission period opens January 2, 2013

• 1st Cycle application submission deadline: March 1, 2013 at 11:59 pm

• Decisions announced (and checks shipped) early June 2013

• 2nd Cycle online application submission period opens July 1, 2013

• 2nd Cycle application sumbission deadline September 3, 2013 at 11:59 pm

• Decisions announced (and checks shipped) early January 2014.

ALL APPLICANTS PLEASE NOTE: When crafting your application, please be mindful of the 2013 Program Timeline above to ensure that the proposed project correlates with the program funding schedule.

Should you have any questions, concerns or technical difficulties with the online application, please contact the Quality of Life department as soon as possible at QoL@ChristopherReeve.org, dvalente@ChristopherReeve.org, rsultzbaugh@ChristopherReeve.org or pmehta@ChristopherReeve.org or call 800-539-7309.

Muscular Dystrophy Association Research Grants Programs

MDA supports research aimed at developing treatments for the muscular dystrophies and related diseases of the neuromuscular system. These are the muscular dystrophies (among which are Duchenne and Becker); motor neuron diseases (including ALS and SMA); the peripheral nerve disorders (CMT and Friedreich's ataxia); inflammatory myopathies; disorders of the neuromuscular junction; metabolic diseases of muscle as well as other myopathies.

RESEARCH GRANT

To be eligible to apply for an MDA research grant, an applicant must:

Hold a Doctor of Medicine (M.D.), Doctor of Philosophy (Ph.D.), Doctor of Science (D.Sc.) or equivalent degree (i.e. D.O.);

Be a professional or faculty member (Professor, Associate Professor or Assistant Professor) at an appropriate educational, medical or research institution;

Be qualified to conduct and mentor a program of original research within their own laboratory;

Assume both administrative and financial responsibility for the grant; and

Have access to institutional resources necessary to conduct the proposed research project.

Proposals from applicants outside the United States will be considered for projects of highest priority to MDA and when, in addition to the applicant's having met the requirements noted above the applicant's country of residence may not have adequate sources of financial support for biomedical research.

NOTE: To apply for a Research Grant, you must be an independent investigator, i.e., not a trainee, not a post-doctoral fellow, not a research assistant, not a research associate and not under the supervision of another person (Principal Investigator/Independent Investigator) who is directing the research.

DEVELOPMENT GRANT

MDA will consider an application for a research grant from a candidate who may be a member of a research team in the laboratory of an independent investigator (Principal Investigator) under whose guidance the applicant will be given flexibility to conduct a neuromuscular disease research project.

To be eligible for a Development Grant, an applicant must:

Hold a Doctor of Medicine (M.D.), Doctor of Philosophy (Ph.D.), Doctor of Science (D.Sc.) or equivalent degree (i.e. D.O.);

Be a member of a research team at an appropriate institution;

Be qualified to conduct a program of original research under the supervision of a Principal Investigator;

Have an acceptable research plan for a specific disease in MDA's program;

Have access to institutional resources necessary to conduct the proposed research project; and

Have eighteen (18) months of post-doctoral research laboratory training at the time of application, but no more than 5 years (60 months).

TENURE

Awards are for either one, two or three years for all grant types.

AWARDS

Funding levels for primary Research Grants are unlimited. Development grants are a maximum of $60,000 per year. Overhead is limited to a maximum of 10% percent of direct costs to be included in the total amount of the grant request.

APPLICATION PROCEDURE

A pre-proposal form must be submitted through proposalCENTRAL® to formally request an application for an MDA research grant. Requests for applications can be submitted anytime prior to the applicable deadline date.

Applications are not open to institutions for general distribution.

ONLY TWO GRANT REVIEW ROUNDS ARE HELD EACH YEAR.

ONLY ONE "LETTER OF INTENT" IS PERMITTED PER GRANT REVIEW ROUND.

DEADLINE DATES

SPRING REVIEW
Letter of Intent: December 15

FALL REVIEW
Letter of Intent: June 15

FOR ONLINE SUBMISSION OF "LETTER OF INTENT"

You will need to register with proposalCentral and request a letter of intent. If approved, you will be given access to the full online application.

CONTACT

Muscular Dystrophy Association
Grants Manager - Research Department
3300 E. Sunrise Drive
Tucson, AZ 85718
(520) 529-2000
(520) 529-5454 (fax)
grants@mdausa.org