American Society of Transplantation/Juvenile Diabetes Research Foundation Faculty Grant (For diabetes-related applications)
This is a two-year grant ($40,000/year) for Junior Faculty (basic or clinical science). This grant is co-sponsored by AST and Juvenile Diabetes Research Foundation International (JDRF) to specifically support research targeted to the application of transplantation to the understanding and treatment of juvenile onset (i.e., type I) diabetes mellitus (e.g., the studies of islet transplantation, autoimmunity, etc.). Appropriate applications in the general pool of the AST Faculty Grants will be considered for the AST/JDRF Grant if no Fellowship Grant applications of sufficiently high quality are reviewed.
To be considered for the AST/JDRF Grant, individuals applying for the AST Basic Science or Clinical science grants, whose proposal pertains to diabetes should check the appropriate box on the front page of the application. Checking this box will ensure that the application is considered for this additional grant which will increase chances for funding. The highest scoring grant application in the general pool of Fellowship Grants that pertains to diabetes will be selected for this grant. Funding of this grant will be dependent upon the budgetary constraints of the two co-sponsoring organizations. The application, review and funding process for the general pool of the AST Faculty Grants will apply to this specialty grant. IMPORTANT DISCLAIMER: The AST will not assume responsibility for any clinical study funded by the AST Awards and Grants Program. Such proposals must be IRB-approved. Any responsibility will be assumed by the P.I. and the funded institution.
Application deadline: Midnight Eastern Time on Friday, November 21, 2008.
American Society of Transplantation 15000 Commerce Parkway Suite C Mt.Laurel, NJ,08054 Phone: 856.439.9986 Fax: 856.439.9982 Email: ast@ahint.com
The 2009 AFAR Research Grants The Program The major goal of this program is to assist in the development of the careers of junior investigators committed to pursuing careers in the field of aging research. AFAR supports research projects concerned with understanding the basic mechanisms of aging. Projects investigating age-related diseases are also supported, especially if approached from the point of view of how basic aging processes may lead to these outcomes. Projects concerning mechanisms underlying common geriatric functional disorders are also encouraged, as long as these include connections to fundamental problems in the biology of aging. Projects that deal strictly with clinical problems such as the diagnosis and treatment of disease, health outcomes, or the social context of aging are not eligible. Examples of promising areas of research include: Aging and immune function Genetic Control of longevity Neurobiology and neuropathology of aging* Invertebrate or vertebrate animal models Cardiovascular aging Aging and cellular stress resistance Metabolic and endocrine changes Age-related changes in cell proliferation Caloric restriction and aging DNA repair and control of gene expression Biology of the menopause Aging and apoptosis Biodemographic analysis of aging Comparative gerontology Evolutionary biological aspects of the biology of aging *Applicants proposing a project in Alzheimer's Disease research, should apply for the Rosalinde and Arthur Gilbert Foundation/AFAR New Investigator Awards in Alzheimer's Disease. (This program is currently under review for renewal in 2009.) It is anticipated that approximately 15 grants of up to $75,000 each will be awarded in 2009. Applicants may propose to use the award over the course of one or two years as justified by the proposed research. Funds may not be requested for overhead or indirect costs. Funding will begin July 1, 2009. Recipients of this award are expected to attend the AFAR Grantee Conference. The purpose of the meeting is to promote scientific and personal exchanges among recent AFAR grantees and experts in aging research. Eligibility The applicant must be an independent investigator with assigned independent space and must be within the first four years of a junior faculty appointment (instructor, assistant professor or equivalent) by July 1, 2009. The AFAR Research Grant Program does not provide support for: Postdoctoral fellows in the laboratory of a senior investigator Investigators who have already received major extramural funding for research on aging (such as an R01 grant) Senior faculty, i.e. at the rank of Associate Professor level or higher Former AFAR Research Grant recipients NIH Intramural program employees Applicants for the 2009 Glenn/AFAR Breakthrough in Gerontology (BIG) award Application Guidelines
Four criteria are used to determine the merit of an application: Qualifications of the applicant; Quality of the proposed research; Excellence of the research environment; Likelihood that the project will advance the applicant's career in aging research. If you are using animals in your research, please review Principles of Animal Use for Gerontological Research. Application Procedures All candidates must submit applications endorsed by their institution (only not-for-profit settings in the United States.) The deadline for receipt of all applications and supporting materials is December 16, 2008 at 5:00 p.m. EST. Please refer to the AFAR instruction sheet and application for complete application procedures. Incomplete applications cannot be considered. Applications are reviewed in two stages: The initial screening takes place in mid-April, after which candidates are advised of the status of their applications via email. A final decision about grant awards is made in early June. The award start date is July 1, 2009. AFAR can provide critiques only for those applications that are reviewed, at the second stage, by their Review Committee. Reporting Requirements Investigators will be required to submit a brief narrative report on the progress of their research five months after the start date of the award. Final narrative and financial reports are required within three months following the end date of the award. American Federation for Aging Research (AFAR) | 55 West 39th Street, 16th Floor | New York, NY 10018 Phone: (212) 703-9977 | Toll-free: (888) 582-2327 | Fax: (212) 997-0330 E-mail: grants@afar.org or info@afar.org
American Association of Diabetes Educators Request for Proposals for Building the Evidence: Problem Solving – Injections
The AADE Education and Research Foundation is offering a $40,000 grant for a research project in the field of diabetes education. The Principal Investigator must be an AADE member at the time of application; team members can be from a variety of disciplines.We are seeking proposals that address problem solving issues and potential solutions surrounding effective insulin/medication injection in patients with a BMI>35 or very low body fat. The overall aim is to identify best practices and effective problem solving solutions for populations who have difficulty with administration of their injections.Proposals must be postmarked by the first business day of November (Monday, November 3, 2008)
Specific AimsCurrently, there is a lack of research on problem solving issues and potential solutions surroundingeffective insulin/medication injection in patients with a BMI>35 or very low body fat. The overall aim is toidentify best practices and effective problem solving solutions for populations who have difficulty withadministration of their injections. The proposed research must examine the problems that individuals atboth the high and low ends of the BMI Index face regarding injection of insulin or other diabetesmedication with a syringe or insulin pen. The findings will be sufficiently robust that they can bedisseminated to diabetes educators via a presentation and/or publication.The Researcher will describe in detail the problem solving and injection intervention(s) that will be used,which method of data collection and analysis will be appropriate for the study, suggested methods fordata collection and analysis follow. The proposed study should also address potential issues, such asinability of patient to see the injection site due to excess abdominal fat and inability to locate anappropriate injection site due to low body fat. Once the problems have been identified and documented,the researchers should implement and evaluate one or more problem solving interventions.Research questions1. What are the knowledge, skills and problem solving behaviors that people with diabetes need toeffectively self-manage their injections?2. What injection techniques should health care professionals use to educate patients to insure that eitherobese (BMI >35), extremely thin (BMI <18.5 or extremely muscular) effectively inject insulin or otherdiabetes medications once they leave the clinical setting?3. What problem solving questions or activities can the CDE employ to ensure that the proper techniqueis used and/or adjustments to technique are made for the target populations?This proposal must address these research questions, specific research aims, and state theintended objectives of the proposed study. Applicants must state the rationale for theirapproach to the problem and state the hypothesis this research is designed to address.SignificanceBriefly describe the background information relevant to this proposal, including a brief evaluationof the existing body of knowledge about the problem. Identify the importance of this study to thefield of diabetes education and/or diabetes nursing practice.
http://www.diabeteseducator.org/Foundation/Grants/CurrentGrants.html
Fanconi Anemia Research Fund Program Announcement: Head And Neck Carcinogenesis Key Dates Release Date: July 1, 2008 Application Submission Date: Ongoing Peer Review Dates: Ongoing Earliest Anticipated Start Date: Ongoing Summary Fanconi anemia is a rare hereditary disease characterized by bone marrow failure, developmental anomalies, a high incidence of myelodysplasia (MDS) and acute non-lymphocytic leukemia (AML), squamous cell carcinoma of the head and neck, and cellular hypersensitivity to cross linking agents. The function of the proteins is largely unknown, but many of them form complexes with each other and in one canonical “pathway” seven or eight of the known Fanconi anemia (FA) proteins bind together in a nuclear complex, a complex apparently required for the monoubiquitination of two of the three proteins not found in the core complex, FANCD2 and FANCI. Once this occurs, FANCD2 and FANCI translocate to damage-induced nuclear foci containing BRCA1, BRCA2 and Rad51. The functions of FANCD2 and FANCI in these nuclear complexes are unclear. Although more than 90% of the research in this field focuses on mechanisms of genotoxicity, a goal of the Fanconi Anemia Research Fund is to encourage investigative approaches dealing with the tissuespecific issues of the FA phenotype. Some have argued that because hypersensitivity to genotoxic stress is a feature of all somatic cells in FA, tissue-specific outcomes (specific epithelial malignancies and bone marrow failure, for example) are less likely to be related simply to genetic instability than to other functions of the protein. In fact, multiple biochemical functions have been ascribed to some of the FA proteins and, in some cases, these functions are cytoplasmic and not nuclear. The role of the Fanconi anemia proteins in protecting normal individuals against sporadic head and neck cancers is entirely unknown. The natural course of the disease in FA patients is unique. The onset of head and neck cancers in patients with Fanconi anemia (age 18-40) is decades earlier than in non-FA patients with this type of cancer and, unlike non-FA patients, the majority of such patients are neither tobacco smokers nor alcohol drinkers. The management of FA patients with this malignancy is also challenging. For example, FA patients may experience potentially lethal toxic effects from radiation and chemotherapy doses conventionally prescribed to patients with head and neck cancers. Therefore, clinical management is limited to surgical approaches and less-than-fully tested pharmacologic modalities that do not lead to DNA damage. This funding opportunity will use the investigator-initiated award mechanism to support work focused on the molecular pathogenesis, diagnosis, and treatment of head and neck squamous cell carcinoma in patients with FA. We expect that the nature and scope of the proposed research will vary from application to application. We expect that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the number, quality, duration, and costs of the applications received. Eligible Applications The goal of this initiative is to foster studies on the molecular pathogenesis, diagnosis and treatment of head and neck cancers in patients with Fanconi anemia. Applications focusing primarily on hematopoietic malignancies, bone marrow failure, developmental anomalies, endocrinopathies, or general functions of the FA proteins in DNA damage and repair responses will not be accepted for review under this RFA. Applications from the following will be considered: Eligible domestic and foreign institutions/organizations, including for-profit or nonprofit, public or private, units of state and local governments, and eligible agencies of the federal government. Eligible principal investigators include any individual with the skills, knowledge, and resources necessary to carry out the proposed research. Applicants may submit only one application. Content and Form of Application Submission Applications must be prepared using the most current Fanconi Anemia Research Fund (Fund) research grant application instructions and forms.
Fanconi Anemia Research Fund, Inc. 1801 Willamette Street, Suite 200 Eugene, OR 97401 Telephone: 541-687-4658 Family Support Toll-Free Line (in United States): 1-888-FANCONI (888-326-2664) Fax: 541-687-0548 E-mail: info@fanconi.org
Career Development AwardAward Description: The American Diabetes Association’s Career Development Awards are designed to assist outstanding Assistant Professor level faculty investigators in conducting diabetes-related research. The award supports an individual’s salary and research project to enable the investigator to advance his/her career as an independent investigator.Support: Awards are $150,000 per year for up to five years, plus 15% allowable indirect costs. Additionally, applicants may request a $25,000 stipend for each of the first two years for additional equipment.Deadline Dates: July 15, 2008 for January 1, 2009 funding and January 15, 2009 for July 1, 2009 funding.
Call the American Diabetes Association at 1-800-DIABETES (1-800-342-2383). Our hours of operation are Monday - Friday, 8:30 AM - 8 PM Eastern Standard Time.Or write to us:American Diabetes AssociationATTN: National Call Center1701 North Beauregard StreetAlexandria, VA 22311
Junior Faculty AwardAward Description: These awards support new investigators who are establishing their independence in diabetes research. Applicants can have any level of faculty appointment up through assistant professor.Support: Awards are up to $120,000 per year for up to three years for direct costs, plus 15% allowable indirect costs. Additionally, applicants can request up to $10,000 per year towards the repayment of the principal on loans for a doctoral degree (MD, PhD, PharmD, DPM or DO). There is not a fixed limit for PI Salary.Deadline Dates: July 15, 2008 for January 1, 2009 funding and January 15, 2009 for July 1, 2009 funding.
ADA-ASP Young Investigator Innovation Award in Geriatric EndocrinologyAward Description: The American Diabetes Association (ADA)-Association of Subspecialty Professors (ASP) Young Investigator Innovation Award in Geriatric Endocrinology provides grant support to new investigators. This program supports entry-level faculty to integrate geriatrics with novel basic, clinical, or health services diabetes research. This award supports pilot and feasibility studies that may lack preliminary data, but offer considerable promise for the cure, prevention, or treatment of diabetes in an aging population.Support: Awards are a maximum of $75,000 per year for up to two years. No indirect costs may be requested.Deadline Dates: July 15, 2008 for January 1, 2009 funding and January 15, 2009 for July 1, 2009 funding.
Research AwardAward Description: These awards provide grant support to both new and established investigators. Applications will be considered in any area that is relevant to the etiology or pathophysiology of diabetes and its complications.Support: Awards are up to $100,000 per year for up to three years. Up to 20% of total costs for PI salary support and up to 15% for indirect costs may be requested.Deadline Dates: July 15, 2008 for January 1, 2009 funding and January 15, 2009 for July 1, 2009 funding.
Mentor-Based Minority Postdoctoral FellowshipAward Description: These awards support minority postdoctoral fellows working with established diabetes investigators. Applications must be initiated and completed by the mentor. Eligible minorities include: African American, Spanish, Hispanic or Latino, American Indian or Alaskan Native, and Native Hawaiian or Pacific Islander. The applying fellow must be a US citizen or permanent resident.Support: Awards are $45,000 per year for up to 3 yrs. No indirect costs may be requested.Deadline Date: January 15, 2009 for July 1, 2009 funding. Please note: January funding is not available for this award.
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