Request for ApplicationsTreatments for Gastrointestinal Dysfunction in Children and Adolescents with ASDAutism Spectrum Disorders (ASD) are behaviorally defined by deficits in communication, social reciprocity, and repetitive stereotypic behaviors. Many children with ASD also experience co-morbid medical conditions that may be treatable. Conditions of particular concern include gastrointestinal (GI) dysfunction, sleep disorders, metabolic disorders, seizure disorders, hormonal imbalances, and nutritional/feeding issues including food allergies and limited food preferences. The prevalence of GI dysfunction and related symptoms, in particular, appears to be elevated in ASD compared to that of the general pediatric population, but the evidence base remains inadequate. The goal of this RFA is to stimulate research to systematically evaluate treatments for GI dysfunction among children and adolescents with ASD.Autism Speaks invites applications for pilot grants to conduct research on treatments for co-morbid GI dysfunction in children and adolescents with autism. These proposals will be reviewed by a committee with expertise in pharmacology, clinical trials research, gastroenterology and clinical science.Research projects may include studies of:• Pharmacological treatments including currently available treatments that are not well studied in autism, or promising new compounds• Biomedical interventions such as nutritional supplements or probioticsProposals should seek to accomplish one or more of the following objectives:• Evaluate the efficacy or therapeutic benefit of pharmacological or biomedical treatments for GI dysfunction in children diagnosed with autism and ASD.• Evaluate the safety of pharmacological or biomedical treatments for GI dysfunction in children and adolescents diagnosed with autism and ASD.• Compare different pharmacological interventions for treating GI dysfunction in children diagnosed with autism and ASD.
Grant Categories and Funds AvailableThis RFA provides funding for pilot studies of treatments for co-morbid GI dysfunction in children and adolescents with autism. Study designs should be clearly defined so as to enable replications and/or expansions of the initial studies. Proposals for open label studies are eligible for submission.Applicants may apply as a single site or as a collaboration between two sites. Autism Speaks will make one multi-site award or two single-site awards as determined by the quality of the applications, the efficient use of the funds requested, and the available financial resources ofAutism Speaks. A lead investigator must be identified for a multi-site award who will apply on behalf of both participating sites.Number of Awards: 1 to 2Award Amounts: $75,000 per site, per year (up to three years)Indirect Costs: An amount not to exceed 10% of direct costs may be given to the Sponsoring Institution for indirect (overhead) costs in addition to the grant amount.Award Period: The grant will be awarded for a maximum period of three years in an amount not to exceed the maximum amount allowable per year based on the type of award funded. While applicants may request funding for a maximum of three years, proposals and applications will be judged, in part, by the efficient use of the funds requested. Applicants must demonstrate the need for the budgeted amounts in their proposal and application.
Investigator QualificationsInvestigators holding full-time tenured or tenure-track faculty appointments or equivalent full-time non-tenure track appointments at accredited academic, medical or research institutions are eligible to apply. A clinician who does not have an academic affiliation is required to collaborate with an individual with a track record in research at an academic or research institution. Applications will NOT be accepted from individuals or proprietary organizations tosupport the research and development of products for profit.Postdoctoral fellows and medical residents in their last year of training are eligible to apply, but must provide documented evidence of appointment to a full-time academic faculty position before an award will be made.
Deadline for applications is December 8, 2008 at 11:59 pm EST (Note new deadline).
Electronic submissions are mandatory. No paper or e-mailed applications will be accepted for upload. For any related inquiries, please contact us at:Adam Liebling, Grants ManagerAutism Speaks2 Park Avenue South, 4th FloorNew York, New York 10016Phone: (917) 475-5071 | Fax: (917) 475-5072 | aliebling@autismspeaks.org
Request for ApplicationsTreatment Research2009 CycleAutism Speaks invites grant applications to conduct innovative clinical studies of evidence-based therapies and novel treatment approaches for children and adults with Autism Spectrum Disorders (ASD). These may include complementary and alternative forms of health care; pharmacological and/or behavioral treatments; and evaluation of the efficacy, safety or therapeutic benefits of interventions.Proposals on the following topics are particularly encouraged: Mediators and moderators of response to treatment; biomarkers that are linked to response to treatment; studies that incorporate biological outcome measures, such as EEG/ERP, fMRI; translational efforts derived from animal models of recovery; novel treatments that target core autism symptoms; infant/ toddler interventions; treatments for adolescents and adults; commonly used treatments that lack efficacy/safety data; treatments that address associated medical conditions, such as sleep, metabolic, and GI problems; service delivery and dissemination research aimed at identifying factors that promote or impede adoption of evidence-based clinical practices. Note: The relevance of the proposed research to ASD must be explicitly stated.
AwardsAutism Speaks will make a limited number of treatment research grants determined by its available financial resources. Each research grants will be for a period of up to three years in an amount not to exceed $100,000 per year. An amount not to exceed 10% of direct costs may be used for Sponsoring Institution's indirect (overhead) costs. The total award including indirect costs cannot exceed the annual maximum award allowed.
EligibilityInvestigators holding full or part-time faculty appointments, professional affiliations or equivalent at accredited academic, medical, osteopathic, chiropractic, research or educational institutions are eligible to apply. Applications will NOT be accepted from individuals or proprietary organizations to support the research and development of products or treatments for profit.Applicants are restricted to one proposal per review cycle as Principal Investigator.
Letter of Intent due: December 1, 2008Proposal due: January 20, 2009Peer review panels: April/May, 2009Notifications: June, 2009Grant start date: July 1, 2009
Society of American Gastrointestinal and Endoscopic Surgeons 2009 Career Development AwardDeadline for Submission: Monday, December 22, 2008PURPOSE & GUIDELINESThe focus of this SAGES Foundation supported award is to provide funding for a young surgeon or surgeon-in-training for the development of critical skills required for their academic career in gastrointestinal and endoscopic surgery. The intent of this award is to delay the start of a faculty role or ongoing residency training for supplemental training/traveling fellowship or intense research time. This grant will provide the awardee with a unique educational opportunity that would not otherwise be available. Awards are conferred on a competitive basis by submission of a grant application, which is reviewed and evaluated by the SAGES Research and Career Development Committee and approved by the Governing Board.AVAILABLE GRANTSThe award will be $60,000 to support travel, salary, and/or tuition. (Note: The salary support portion of the grant will be taxable)GRANT GUIDELINESEligible applicants must be SAGES candidate members (including residents and Fellows), or members early in their faculty appointment (within five years of completed training).This award is not intended to be used for research supplies. The time commitment for the project is to be at least 6 months.Awardees will summarize their experience at the SAGES Annual Meeting and submit results to Surgical Endoscopy or Mini-SCOPE.Examples of successful proposals could include, but are not exclusive to the following: * Salary support for basic or clinical investigation by the awardee. * Salary support for intensive training in a clinical area (interventional endoscopy, NOTES, advanced laparoscopic techniques). * Salary support for research, management, leadership or related training (outcomes, legislative, safety, financingINSTRUCTIONS – NEW FOR 2009SAGES Career Development Award applications must be submitted online and you must be logged in as a member to submit a grant application. Online applications will open shortly, check back soon.DEADLINE - Grant Proposals must be received by the SAGES office by Monday, December 22, 2008 at 5PM Eastern. The applications will be reviewed in late January and the top three candidates will interview via phone in February. A decision for funding will be made by February 2009 and will be announced during the award ceremony at the SAGES 2009 Annual Meeting in Phoenix, Arizona April 22-25, 2009.
Society of American Gastrointestinal and EndoscopicMailing Address:SAGES11300 West Olympic BoulevardSuite 600Los Angeles, CA 90064 Phone and Fax Numbers:Administrative Office Phone: 310-437-0544Administrative Office Fax: 310-437-0585
Clinical Research GrantsIn 2009, the American College of Gastroenterology will again offer Clinical Research Awards of up to $35,000 for original research in clinical gastroenterology. At least one of the investigators must be an ACG member or trainee member at the time of submission of the grant proposal. Note that physicians in training (interns, residents, fellows) are eligible to apply provided that the work is conducted under the preceptorship of a more senior or experienced investigator. In order to assure diversity among recipients, no more than two Clinical Research Awards will be granted to former or current principal investigators on R01, P01, U01, VA Merit Awards or Hughes grants, or to those who hold the position of full professor at an academic institution. Awardees will be selected based on feasibility, scientific and clinical significance, originality and anticipated contribution of the research to clinical practice. Applications will also be evaluated on the availability of adequate resources, including personnel and facilities.2009 ACG Clinical Research Award DeadlineAn original and six (6) copies of the completed application package for the Clinical Research Award must be received by the deadline of Friday, December 12, 2008. Awardees will be notified by April 1, 2009 with the award period to begin in July 1, 2009.
American College of Gastroenterology P.O. Box 342260 Bethesda, MD 20827-2260 (301) 263-9000
Junior Faculty Development GrantsThe American College of Gastroenterology is seeking applications for the 2009 ACG Junior Faculty Development Award. The primary goal of this career development grant of $75,000 per year for each of two years is to assist promising clinical researchers to develop research and careers that have a direct bearing on clinical gastrointestinal practice. This includes assistance to a junior faculty investigator to ensure that a major portion of the investigator's time is protected for clinical research. The Junior Faculty award provides support for junior investigators working toward independent careers in clinical research related to gastroenterology or hepatology.To be eligible for the Junior Faculty award, applicants must be physicians who hold full-time faculty positions at a North American (U.S. or Canada) university, medical school, or other health care institution at the time of funding of the application, should it be approved. Applicants also must be members of the ACG at the time of application. This award is not intended for fellows, but for junior faculty who have demonstrated unusual promise and have some record of accomplishment in research. Established investigators are not eligible. Candidates must devote at least 50% of their effort to clinical research related to gastroenterology or hepatology.Junior Faculty Development Award DeadlineAn original and six (6) copies of the completed application package for the Junior Faculty Award must be received by the deadline of Friday, December 12, 2008. The award period will begin July 1, 2009.
Medical Student Research Initiation GrantLength of Award: 2-3 MonthsAmount: $4,000Deadline: April 1Purpose: To provide opportunities for Medical Students to participate in clinical orlaboratory-based research focused on diseases of the colon, rectum and anus.Eligibility Requirements:• Medical Student in a US or Canadian Medical School.
American Society of Colon and Rectal Surgeons85 W. Algonquin Rd., Suite 550Arlington Heights, IL 60005Phone: 847-290-9184Fax: 847-290-9203Email: ascrs@fascrs.org
General Surgery Resident Research Initiation GrantLength of Award: 1-2 yearsAmount: $20,000/yearDeadline: April 1Purpose: To attract General Surgery Residents or recent Graduates of such programsinto the field of Colon and Rectal Surgery by providing opportunities to engage inclinical or laboratory-based research focused on diseases of the colon, rectum and anus.Eligibility Requirements:• General Surgical Residents or recent Graduates of a US or Canadian approvedGeneral Surgery Training Program.
The Eli and Edythe Broad Foundation created the Broad Medical Research Program (BMRP) for Inflammatory Bowel Disease (IBD) Grants in 2001.IBD refers to two chronic inflammatory gastrointestinal disorders: Crohn's disease and ulcerative colitis. Although numerous scientific advances have been made in understanding and treating IBD, the precise cause, successful treatment and prevention of IBD remain unknown.The Eli and Edythe Broad Foundation, through the BMRP, provides 40 percent of all private funding for IBD research in the United States. Our approach is different than many traditional scientific and medical funding organizations. We fund early stage investigation – with the goal that innovative ideas need financial support for early testing to ultimately lead to effective treatment, diagnosis and prevention of IBD.The BMRP provides rapid funding to investigators working in non-profit organizations worldwide for up to two years for basic or clinical IBD research projects that: * Are innovative * Are in the early stages of exploration * Will improve the diagnosis, therapy or prevention of IBD in the near future; and * Will lead to longer-term funding by more traditional granting agenciesThe BMRP provides funding to generate pilot research data, rather than serving as the final grant source for a research project. Grantees are encouraged to generate sufficient preliminary data in the first year in order to compete successfully for continuation funding from us and/or other sources.A grantee may receive second-year funding from the BMRP if the researcher demonstrates maximal progress in the first year of the grant, validates the original research premise and demonstrates a clear need for additional preliminary data.Because we believe that great ideas could come from non-traditional sources, we encourage basic and clinical investigators and scientists not currently working in IBD and interdisciplinary teams to apply.
There is a two-step process for requesting funding from the Broad Medical Research Program (BMRP) for Inflammatory Bowel Disease:1. The first step is to submit a Letter of Interest. Instructions and format for Letters of Interest may be found under “How to Apply.” Decisions on Letters of Interest are based on external expert review of the proposal and usually are made within four to six weeks.2. If the BMRP is interested in pursuing a project, an invitation is extended to submit a full grant application. At that time, the grant application instructions and forms are sent to the Principal Investigator. Decisions on grant applications are made based on external review by subject experts and usually take eight to 10 weeks.There are no deadlines or specific dates for applications. Proposals are accepted and reviewed year-round. Revised proposals may only be submitted at the request of the BMRP.Special Requests for ProposalsThe BMRP is currently soliciting proposals in two areas of research:Differences in IBD incidence between developing and developed countriesThe BMRP is funding innovative research into the possible reasons for low and high incidence of IBD in different areas of the globe. Proposals should be exploratory in nature or designed as pilot. The research should shed light on factors that may influence low versus high global areas of prevalence of the disease. The research should ultimately be helpful in improved understanding of the etiology of IBD and the factors that enhance or prevent the genesis of the disease.IBD and Diabetes MellitusThe BMRP is interested in early stage exploratory innovative research proposals to investigate the similarities and differences between inflammatory bowel diseases (IBD) and diabetes mellitus (DM).Proposals should be exploratory in nature designed as pilot projects researching possible commonality in the etiopathogenesis between IBD and DM. Human or animal model studies are welcomed.
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