Doris Duke Clinical Scientist Development Award
The purpose of the Doris Duke Clinical Scientist Development Award Program is to provide support formentored research to junior faculty members with an M.D. or M.D./Ph.D. (physician-scientists) workingin any disease area as they begin their careers as independent clinical researchers.The early stage of career development, when a researcher is transitioning from working in a mentor’slaboratory to setting up an independent research program and obtaining grant funding, is a criticalperiod. It is often more difficult for physician-scientists who are conducting clinical research to makethis transition than it is for other researchers because these individuals typically have to balance thedemands of seeing patients with those of conducting research. Those demands, together with thecomplexity of today’s research environment and the pace of progress, make it particularly challenging tomaintain the knowledge base needed to be both a clinician and a researcher. Nevertheless, the role of thephysician-scientist in providing the bridge between the clinic and the laboratory is critical for the timelytranslation of basic research findings into therapeutic approaches and for the transfer of clinicalknowledge back to the laboratory.
The 2009 Clinical Scientist Development Awards are being offered to eligible junior faculty members ata funding level of $135,000 per year for 3 years. It is DDCF’s hope that by providing stable support at acritical career juncture for physician-scientists, the Clinical Scientist Development Award willencourage physicians to pursue careers in clinical research.
Definition of Clinical ResearchFor the purposes of this award program, clinical research is defined as research conducted with humansubjects with direct application to the prevention, diagnosis, treatment, or cure of any human disease.The Foundation’s definition of clinical research includes:• Studies on the etiology and pathogenesis of human disease• Therapeutic interventions• Clinical trials• Epidemiological studies• Disease control research• Operations and implementation research
Eligibility of NomineeThis program is specifically intended to help physician-scientists make the critical transition fromtraining to independence as clinical investigators.It is the responsibility of each institution to ensure that its nominees meet all of the eligibilityrequirements. The replacement of nominees will not be permitted.Applicants must:• Be a physician-scientist conducting clinical research in any disease area;• Have received an M.D. or a foreign equivalent from an accredited institution;• Be working in a U.S. degree-granting institution, but do not have to be a U.S. citizen;• Have a full-time faculty level position not higher than the Assistant Professor level; and• Have been appointed to their first full-time faculty level position between January 1, 2004 andJanuary 1, 2009. (All full-time post-fellowship Instructor level positions will be considered full-timefaculty level appointments).
Online Submission of NominationsInstitutions nominating candidates must submit their nominations using the online system athttp://www.ddcf.org/apps/csda/index.asp on or before 5 pm EST on November 5, 2008. Before enteringthe online system, please be sure that you gather all the required information listed in the instructions fornomination which are available at http://www.ddcf.org/mrp-csda. All of an institution’s nominationsmust be entered at the same time. Nominations submitted by other methods will not be accepted. It is theresponsibility of the institutions to ensure that candidates nominated
American Society of Transplantation Clinical Science Fellowship Grant
Application deadline: Midnight Eastern Time on Friday, November 21, 2008. The goals of the AST Fellowship Grants are: To foster training of new young investigators who have the potential to contribute to our understanding of transplant science/immunobiology and/or treatment of transplant recipients. To foster research that is of high merit. To encourage high quality applicants who want to develop a career in academic transplantation. The AST Fellowship Grants are 2 year grants of $40,000/year, designed to provide salary support for individuals who have spent two years or less (at the time of the application) performing research in the area of transplantation since obtaining their last post-doctoral degree (PhD, MD or equivalent). See Eligibility Requirements for more detailed information. The AST Fellowship Grant applications are submitted in one of two primary categories and one specialized category (AST/JDRF grant). The Grants all share the same eligibility requirements, application and review process. AST Clinical Science Fellowship Grant
The Clinical Science Fellowship Grants relate to the observation and treatment of patients. Clinical science grants cover three main categories: Clinical Trials, Clinical Outcomes, and Translational Research that involves materials from human patients. Clinical Trials: should be designed to answer specific question(s) about new therapies or new ways of using known treatments. Preference will be given to prospective studies. Clinical Outcomes or Observational Studies: should be designed to better define the causes and/or consequences of pathological or biological processes in transplantation. Retrospective studies may be appropriate. However, proposals that analyze registry data (e.g. data collected by the United Network for Organ Sharing) are expected to test unique hypotheses or employ new data or methodologies. The analysis, including the statistics, should be performed by the applicant and not by the providing data registry group. The Influence of Public Policy on Transplantation: such studies are designed to evaluate the effects of public health care policy on health care delivery, medication choices, and/or outcomes pertaining to transplant recipients. Translational Research: projects involve human tissue or other biologic material for in vitro examination to address a clinical issue related to transplantation. In general, these studies should link the in vitro results to other data or outcomes from the same patients to be considered a clinical research fellowship proposal. IMPORTANT DISCLAIMER: The AST will not assume responsibility for any clinical study funded by the AST Awards and Grants Program. Such proposals must be IRB-approved. Any responsibility will be assumed by the P.I. and the funded institution.
American Society of Transplantation 15000 Commerce Parkway Suite C Mt.Laurel, NJ,08054 Phone: 856.439.9986 Fax: 856.439.9982 Email: ast@ahint.com
American Society of Transplantation Clinical Science Faculty Development Grant This is a two-year grant ($40,000/year) for Junior Faculty The goal of the AST Faculty Development Grants is to promote the careers of young independent investigators within the first 5 years of their first faculty appointment (see eligibility criteria), by providing funds allowing them to expand on preliminary research findings that will become the basis for individual research or career development awards from the NIH, VA, or equivalent agencies. Clinical Science Grants cover three main categories: Clinical Trials, Clinical Outcomes, and Translational Research that involves materials from human patients. Clinical Trials: should be designed to answer specific question(s) about new therapies or new ways of using known treatments. Preference will be given to prospective studies. Clinical Outcomes or Observational Studies: should be designed to better define the causes and/or consequences of pathological or biological processes in transplantation. Retrospective studies may be appropriate. However, proposals that analyze registry data (e.g. data collected by the United Network for Organ Sharing) are expected to test unique hypotheses or employ new data or methodologies. The analysis, including the statistics, should be performed by the applicant and not by the providing data registry group. Translational Research: projects involve human tissue or other biologic material for in vitro examination to address a clinical issue related to transplantation. In general, these studies should link the in vitro results to other data or outcomes from the same patients to be considered a clinical research faculty proposal.
Application Deadline: MIDNIGHT Eastern time ON FRIDAY, November 21, 2008 IMPORTANT REMINDERS All applications for the AST Faculty Grants must be completed by Midnight Eastern Time on Friday, November 21, 2008. The application site for the AST Awards and Grants Program will automatically shut down after the deadline. No application or supplementary documents will be accepted after the submission deadline. Letters of recommendation with original/electronic signatures on institutional letterhead must be uploaded electronically to the online application. Original letters of recommendation must be mailed to the AST National Office, postmarked by the submission deadline and have an original signature on institutional letterhead. Confirmation e-mails will be sent out once an application is complete.
DISCLAIMER: The AST will not assume responsibility for any clinical study funded by the AST Awards and Grants Program. Such proposals must be IRB-approved. Any responsibility will be assumed by the P.I. and the funded institution. American Society of Transplantation 15000 Commerce Parkway Suite C Mt.Laurel, NJ,08054 Phone: 856.439.9986 Fax: 856.439.9982 Email: ast@ahint.com
The American Laryngological, Rhinological and Otological Society, Inc., aka The Triological SocietyThe Triological Career Development Awards provide support for the research career development of otolaryngologists-head and neck surgeons who have made a commitment to focus their research endeavors on patient-oriented research such as clinical trials, translational research, outcomes research and health services research. Five non-renewable awards in the amount of $40,000 each are funded annually for a one or two year project period.
The purpose of this award is to provide support for the research career development of otolaryngologistsheadand neck surgeons who have made a commitment to focus their research endeavors on patient-orientedresearch, e.g., clinical trials, translational research. Projects sponsored under this grant programmust have specific application in the field of otolaryngology-head and neck surgery.ELIGIBILITYOtolaryngologists-head and neck surgeons who hold full-time, part-time or contributed service medicalschool faculty appointments and who have made a commitment to focus their research endeavors onpatient-oriented research may apply. Applicants must be sponsored by the Chair of his/her division ordepartment and by an official representative of the institution which would administer the award and inwhose name the application is formally submitted. Applicants must clearly indicate in the “Other Support”section of the application whether support for the submitted project is being sought from other fundingagencies or organizations. Applicants currently holding research career development awards from NIH orother funding agencies are eligible to apply, however, applicants must indicate how the supplementalfunds from the Triological Society’s research grant will be utilized.CONDITIONSResearch training supported by this award may be related to any research questions relevant to thespecialty of otolaryngology - head and neck surgery, as long as it is demonstrated that the training willhave a direct impact on the applicant’s ability to pursue his/her long-range research objectives. Proposalswhich aim to introduce new knowledge and methodology from other disciplines to research inotolaryngology - head and neck surgery are encouraged. The recipient is expected to devote at least40% of his/her time to the proposed research and research training activities during the period of theaward. The recipient is expected to submit an abstract to be considered for presentation at a TriologicalSociety meeting at the conclusion of the award period. The Society shall have the right of first refusal inregards to publishing the results of any investigation support by this award in its journal, TheLaryngoscope. Applicants must obtain letters of support/understanding from all key personnel on theproject.TERMS1. Amount: $40,000 maximum2. Period: 12 months-24 months, at investigator’s discretion, non-renewable
All applicants must submit a Letter of Intent online no later than midnight Eastern Standard TimeDecember 15. The letter of intent includes the title of the project, the principal investigator, and anabstract of the work. This will facilitate planning review requirements.
The Parker B. Francis Fellowship in Pulmonary Research is intended to support the development of outstanding investigators who plan careers in pulmonary research. We seek to help them as they make the transition to independent, self-supporting, faculty members. Parker B. Francis Fellowship grants are awarded to institutions for the purpose of providing stipends, fringe benefits, and modest travel expenses in support of qualified post-doctoral fellows or newly appointed assistant professors. Award recipients will thereby be enabled to devote the major part of their professional effort to research related to pulmonary disease and lung biology. Grants are made for three years of support. It is permissible to maintain support for the awardee as he or she moves from fellowship to faculty status. Awards are made to institutions on behalf of the fellows and can be transferred to other institutions only under special circumstances with prior approval from the Director of the Fellowship Program. Fellows supported by a Parker B. Francis Fellowship must be assured of having at least 75 percent of their time available for research. This means that a total of no more than three months per year may be spent in clinical or other non-research activities.
GENERAL INFORMATION APPLICANTS The ideal candidate is one with evidence of strong aptitude in research and who is in transition from post-doctoral trainee to independent investigator. It is essential that there be evidence of accomplishment and proficiency in research. Few applicants who are just beginning research training and have only one or two research publications are funded. Candidates with greater than seven years since the doctoral degree should include reasons for continued training. Candidates may hold any relevant doctoral degree (e.g., M.D., Ph.D., Sc.D., D.V.M., Dr. P.H.). Fellowships are restricted to US, Canadian and Mexican citizens or permanent residents. However, foreign nationals who document their initial steps toward permanent residence in the US, Canada or Mexico will also be considered. Documentation should include a description of steps already taken toward application for long-term residency or citizenship. MENTORS Mentorship of the fellow by an established investigator is required. Any established faculty scientist at a university or a not-for-profit research institution may mentor a candidate for fellowship. Mentors at government or corporate laboratories are not eligible. The mentor should be in a position to guarantee that 75 percent of a fellow's time is available for research. The mentor should be committed to fostering the candidate's career advancement and should be the primary scientific advisor. Secondary scientific mentors at the same or a different institution are encouraged but not required. Their roles should be described in the body of the application. Many fellows spend some portion of their fellowship years working with a secondary mentor at another institution. INSTITUTIONS There are no restrictions regarding discipline or department. Clinical or basic science departments are suitable; however, it is expected that the proposed research will focus on lung biology or lung disease. Awards are limited to institutions located in the US, Canada and Mexico. Each department may submit only one application annually and is limited to a maximum of two active fellowships at any one time. NOTES ABOUT OTHER GRANT SUPPORT Having an NIH K series or similar award at the time of application makes one ineligible for a PBF Fellowship. However, once awarded, a PBF Fellow may accept such a grant, as long as the basic requirements of the PBF Fellowship are met (75 percent of time available for research and PBF funds used only for salary and travel). Most importantly, the area of lung research pursued should remain the same. Previous individual or institutional NIH or MRC training grants do not make one ineligible, although they must be relinquished if a PBF Fellowship is awarded. Individuals are ineligible for a PBF Fellowship if they are the principal investigator on an NIH RO1 or similar research grant when applying for a PBF Fellowship. But Fellows in their second or third year may have their own NIH RO1 or similar grant. In fact, obtaining research grants is an appropriate goal for PBF Fellows. Since fellowship funds are restricted to the Fellow's salary and travel, in some cases it may not be possible to utilize the full level of PBF Fellowship support. Awards will not be given if either the fellow or mentor currently holds funding from the tobacco industry, even if the tobacco monies will not be used to support the PBF sponsored research. APPROPRIATE TOPICS A broad array of approaches to lung biology and respiratory medicine, ranging from cell and molecular studies, to those involving epidemiologic and clinical aspects of human subjects are appropriate. We also encourage applications from pulmonary medicine specialists interested in pursuing research in bioethical aspects of pulmonary medicine or critical care. Potential topics include, but are not limited to, the ethics of clinical trials in critical care, end-of-life decisions and resource allocation. The context of all these topics should be pulmonary biology and lung disease. Applicants must meet all the eligibility standards. Mentors and/or applicants considering whether a particular area is appropriate are encouraged to discuss potential projects with the Director of the PBF Fellowship Program in Seattle, Washington (trmartin@u.washington.edu).
MAILING ADDRESS Thomas R. Martin, M.D. Director Parker B. Francis Fellowship Program Pulmonary Research Laboratories VA Puget Sound Health Care System 1660 S. Columbian Way, 151L Seattle, WA 98108 DEADLINE Applications must be received no later than Friday, October 17, 2008.
American Association of Neurological Surgeons and Congress of Neurological Surgeons Section on Disorders of the Spine and Peripheral Nerves Research & Fellowship Awards
DEADLINE FOR ALL SUBMISSIONS: December 1, 2008
FELLOWSHIP FUNDING: Cahill Fellowship spine or peripheral nerve $30,000 Cloward Fellowship spine or peripheral nerve $30,000 Crockard International Fellowship spine $5,000 Sonntag International Fellowship spine $5,000 For further information and submission of forms, please contact: Peter C. Gerszten, MD, Department of Neurosurgery, University of Pittsburgh Physicians, 200 Lothrop Street, STE B-400 PUH, Pittsburgh, PA 15213, (412) 647-0958 or via email at gersztenpc@upmc.edu. RESEARCH FUNDING: Apfelbaum Award spine $15,000 Kline Award peripheral nerve $15,000 Larson Award spine or peripheral nerve $30,000 The AANS/CNS Section on Disorders of the Spine and Peripheral Nerves has established three Research Grants. Depending upon the quality of the award submissions, there may be one award in each category annually. These awards are intended for primary investigators with proposed research requiring national level funding, to support the preparation of grant proposals and external consultations and to assist in the development of the proposal, planning meetings, and the collection of pilot data. Work that can be completed without such support (such as literature review and preliminary protocol design) should be completed before applying for these awards. The format of the proposal should follow that of the NIH grant package. The applicants should clearly define their specific aims, include a pertinent literature review, describe the proposed methodology and plan for analysis of data. This part of the proposal should not exceed 10 double-spaced pages. A detailed budget and budget justification should also be included. The budget should not include salary support for the primary investigator or co-investigators. Institutional indirect costs are also not to be met using the awards. Application details for research grants may be downloaded here. For further information and submission of forms, please contact: Peter C. Gerszten, MD, Department of Neurosurgery, University of Pittsburgh Physicians, 200 Lothrop Street, STE B-400 PUH, Pittsburgh, PA 15213, (412) 647-0958 or via email at gersztenpc@upmc.edu. SPINE CLINICAL TRIAL PROPOSAL AND FELLOWSHIP AWARD: Spine Clinical Trial Proposal - $500 Spine Clinical Fellowship Award - $50,000 The AANS/CNS Section on Disorders of the Spine and Peripheral Nerves is pleased to announce the creation of a clinical trials fellowship award to promote clinical trials in spine. Neurosurgical residents/ fellows/ junior faculty are eligible to submit proposals ($500). Only junior faculty are eligible for the Fellowship Award ($50,000). The objective of this Fellowship is to foster the spirit of team-building necessary for executing multi-center studies, which are critically needed in neurosurgery in general, and spinal surgery in particular. Please send all proposals and questions to Zoher Ghogawala, MD by email at zoher.ghogawala@yale.edu. OUTCOMES COMMITTEE AWARD: The Outcomes Committee Award is presented annually by the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves to a neurosurgical resident or BC/BE neurosurgeon in North America who authors an outstanding abstract presenting the results of a clinical investigation in the area of spine or peripheral nerve disorders, that demonstrates sound methodological design and includes evaluation of patient-oriented outcomes as the primary endpoint. The recipient of the award will be selected by the members of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves Outcomes Committee. The award is gift from The David and Jean Wallace Fund. The recipient will receive a $2,000 honorarium to help cover the expenses of attendance at the Joint Section annual meeting. Abstracts to be considered should be identified on the annual meeting abstract submission form and submitted prior to the deadline. Deadline: same as abstract submission deadline. RESIDENT AWARDS: The Mayfield Awards are presented annually by the Joint Section on Disorders of the Spine and Peripheral Nerves to the neurosurgical residents or BC/BE fellows in North American training who author the outstanding manuscripts detailing a laboratory or clinical investigation in the area of spinal or peripheral nerve disorders. This award is also applicable to individuals in DO training programs. The manuscript for this award is presented by attaching to the related abstract in the call for abstract process. Two awards are available, one for clinical research and one for basic science research. Each recipient will receive a $1,000 cash award and an honorarium up to $2,000 to cover the expenses of attendance at the annual meeting of the Section. Abstracts to be considered for the Mayfield Award should be identified as such on the annual meeting abstract submission form and submitted prior to deadline. For further information and submission of forms, please contact: Peter C. Gerszten, MD, Department of Neurosurgery, University of Pittsburgh Physicians, 200 Lothrop Street, STE B-400 PUH, Pittsburgh, PA 15213, (412) 647-0958 or via email at gersztenpc@upmc.edu. Deadline: same as abstract submission deadline.
Grant Information The Research Grant Cycle Berrylin J. Ferguson, MD Research Chairman Research funding has not only become an AAOA Foundation priority, but due to investment management and generous donations, the organization has developed significant funds that can be committed to research. My priority has been to develop a standardized approach to research funding that allows for a wide range of applicants, supports the AAOA/F goals, and is accountable to the Board and the membership. To this end, a standard AAOA Foundation Research Funding Application has been developed. Grant recipients have been made accountable for disbursed funds, and presentations are not being considered for grants unless a completed manuscript is received. The next step was to develop a repeating research cycle that will allow us to advertise for high quality applicants and will permit a seamless flow from the point where the Foundation determines research priorities to the finished report by the investigator. The following timeline has been developed for our annual cycles. We have expanded this cycle to include a second review cycle to encourage more grant applications and to accommodate the resident training cycle. We are now accepting applications for the new June 30th review deadline. Research Funding Cycle COSM Foundation reviews research committee reports of progress made in funded studies, announces the studies funded for the present year (recipients were alerted Feb. 15th), and determines priority of research needs for the immediate and future cycles. When a study has concluded, plans for follow-on work and publication are presented. July Interest on AAOA Foundation research accounts is posted, allowing a decision on the amount of funding available for the next grant cycle. August/September Money available is placed according to the May Foundation/ Board priorities into grants available for competitive research applications. Interim 6 –month report from funded projects due to the research coordinator. Annual Meeting Request for applications (RFAs) are circulated at the meeting, in both AAOA Foundation and AAO-HNS literature. Progress of funded studies is reviewed. Presen-tations and publications of completed studies are announced. December 31/June 30 Deadline for applications for the funding cycle. Feburary 15/July 15 Grants awarded and recipients notified; annual reports from funded projects are due to the research chairman. The AAOA Research Committee reviews grant applications twice a year. The grant deadlines are December 31st and June 30th. Funding priority is given to: Studies which are of clinical interest to the member-ship and utilize AAOA techniques. Basic science and clinical pilot studies ($5000 or less) which can generate preliminary data to support applications to larger funding sources such as the AAO-HNS CORE research program or the NIH. Larger funding requests will be considered at the discretion of the committee, however indirect costs and investigator salary support will not be provided. All funded studies are expected to submit the results for consideration for presentation at the AAOA annual meeting and for publication in the journal of the AAOA–Otolaryngology–Head and Neck Surgery. Membership in the AAOA is not required for consideration of research proposal, but is encouraged. Residents are encouraged to apply for these grants. Potential project themes are listed. Since these are pilot programs, each protocol should include 20 subjects (10 subjects and 10 controls), be completed in 12 months, and will be eligible for up to $5,000 of funding. Studies which have controls, preferably double-blinded, will be given priority. Potential Pilot Project Themes I. Testing Techniques IDT (intradermal dilutional titration) IPDFT (intradermal progressive dilutional food test) In vitro (RAST or ELISA) Results from use of these techniques Comparison with other techniques –ie, prick or multi-test prick Technical details of sensitivity or specificity of techniques Especially helpful would be comparison of our techniques with allergen challenges–intranasal, oral, intrapulmonary, conjunctival, etc.) II. Incidence of Specific Allergies (using AAOA Techniques)
Incidence of inhalant test positives in a geographic area or specific population. Incidence of food test positives in an ethnic population. Incidence of either positive inhalants or foods in specific ENT diseases. Asero R., Bottazzi G. (Annals Allergy Asthma Immunology 2001; 86:283-5) recently reported that over 23% of patients withpolyps had Candida allergy compared to < 1% of patients with seasonal allergic rhinitis. Studies such as this using intradermal dilutional techniques would be very straightforward in application (eg,non-polyp chronic rhinosinusitis, vs. polypoid rhinosinusitis, etc). III. Use of Allergy in Disease Management (especially double-blinded trials) 1. Does Allergy Management by Environmental Controls and Immunotherapy make a difference in: Complications Need for Surgery Subsequent surgeries 2. Does Allergy Management by Environmental Controls and Immunotherapy make a difference in: Sinus Cripples Nasal Polyps Chronic Otorrhea External Otitis (esp. Rx with TOE fungal antigens) Chronic Tonsillitis Chronic Laryngitis IV. Specific Therapeutic Interventions (especially double-blinded trials) Histamine for headache, vertigo, polyps, or other uses. Immunotherapy for specific diseases (rhinosinusitis, serous otitis, chronic laryngitis, Meniere’s disease, etc. Food Diets for specific diseases (GERD, postnasal drip, migraine, urticaria, eczema, asthma, etc). Food Immunotherapy, with or without food diets. Heparin or low mol. wt. Heparin animal study comparing efficacy of both forms. Topical for chronic external otitis IV for acute allergy emergency Anaphylaxis Asthma Urticaria Flu vaccine as a generic treatment for viral URIs or herpes simplex. Combined use of Immunotherapy with a leukotriene modifier versus single therapy with either, for nasal obstruction or polyps, or for urticaria. Combined use of Immunotherapy with an intranasal steroid spray versus single therapy with either, for nasal obstruction or polyps. Call 202-955-5010 or email info@aaoaf.org for more information on the AAOA/F.
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