18 funding opportunities found in this category. Change the order of results: Newest First Oldest First Expiring Soonest Expiring Latest Lowest Award to Highest Highest Award to Lowest
Autism Speaks Request for Applications: Treatment Research Grants: Full- and Pilot-Level 2012 Cycle
Letter of Intent due: February 23, 2012, 8:00 PM Eastern Autism Speaks invites both Full- and Pilot-Level Treatment research grant applications to conduct innovative clinical studies of novel interventions for individuals with Autism Spectrum Disorders (ASD) throughout the lifespan. These may include medical approaches including complementary and alternative forms of health care and pharmacological treatments, as well as behavioral and/or psychosocial interventions, and evaluation of the efficacy, safety or therapeutic benefits of all types of interventions. Also appropriate are animal model studies that test the effects of novel compounds for reducing autism symptoms.
For all RFAs, Autism Speaks is focusing on a set of targeted research priorities for 2012. All treatment study projects will be required to demonstrate direct relevance to at least one of these targeted research priorities:
1. Understand environmental risk factors and their interaction with genetic susceptibility to enable prevention and improve diagnosis and treatment
2. Discover biomarkers that can improve risk assessment and subtype stratification that will allow for an individualized approach to treatment
3. Improve quality of life through more effective medicines, behavioral interventions, and technologies
4. Enhance diagnosis and treatment of underserved and under-studied populations, specifically,
• Nonverbal persons with ASD • Ethnically-diverse and/or low resource communities • Adults • Those with medical co-morbidities
5. Disseminate and implement evidence-based clinical practices to the broader community worldwide IMPORTANT: The relevance of the proposed research to ASD and Autism Speaks’ research priority areas must be explicitly described in the Letter of Intent (LOI) and full application.
Awards Autism Speaks will make a limited number of treatment research grants determined by the available financial resources. Full-level research grant 1-3 years $150,000/year maximum
Pilot-level research grant 1-2 years $60,000/year maximum
Autism Speaks utilizes a web-based application system for their grant submissions. All applications must be submitted through this system. It is imperative to indicate whether the submission is for the Full- or Pilot-Level Treatment research option.
Research Inquiries research@autismspeaks.org
Epilepsy Therapy Project/Epilepsy Foundation New Therapy - Commercialization Grants Program
Letter of Intent due: March 1, 2012, 11:59 PM ET
If LOI is accepted, APPLICATION is due: April 12, 2012, 11:59 PM ET
The New Therapy - Commercialization Grants Program is a unique partnership between two leading epilepsy non-profit organizations, the Epilepsy Therapy Project and the Epilepsy Foundation. The mission of the New Therapy - Commercialization Grants Program is to drive the development of new therapies for epilepsy, accelerating the advancement of research from the laboratory to the patient. Funding is provided to academic and commercial groups worldwide. The Program seeks to advance the development of new therapies including but not limited to medicines, biologics or devices. All proposals must demonstrate a clear path from the lab to the patient and are evaluated with consideration for their potential value to patients, likelihood of successful development including regulatory approval and the timeframe of development. The Program also encourages 1:1 matching grants to academic and commercial entities to support the commercialization of novel approaches to the treatment of epilepsy. Preference will be given to proposals that already have a commercial partner engaged to assist with development, and to proposals that have committed or matched funding from a sponsoring institution, commercial partner or other third party source.
Applicants must demonstrate background work beyond the basic science discovery stage.
Areas of interest include:
Novel approaches to treatment. Platform technology to advance screening techniques that can be utilized by multiple laboratories, including utility of techniques for early proof-of-concept trials. Adaptation of treatment in development for another therapeutic area to assess utility for epilepsy (while maintaining patent protection).
All proposals will be evaluated by our Business and Scientific Advisory Boards, as described below:
Proposals are rated on the likelihood of success by the Business Advisory Board as:
Intellectual Property Strategy & Status; Freedom To Operate Can this Get to Patients: Investment Potential & Likelihood of Ongoing Funding Support Probability of Success / Time Factor Fit with Program Mission / Patient Impact Overall Impression
Proposals are rated on the likelihood of success by the Scientific Advisory Board as:
Quality of Science Probability of Successful completion of milestones / outlined program Timeframe of Success Fit with Program Mission / Impact on Patients Overall Impression
These grants are awarded only to programs that have progressed beyond the basic science discovery stage. Investigators are strongly advised to have their compounds screened, as appropriate, by the NINDS ASP Program, http://www.ninds.nih.gov/research/asp/index.htm. Investigators are expected to have an established record of achievement in the area. Full intellectual property (IP) rights (composition of matter) are preferred over method of use IP. Clinical programs must have a reasonable protocol and sample size to assure that the results will be meaningful; studies of patients should describe the type of seizure/epilepsy that will be investigated. Device programs should present novel concepts for treatment.
Confidential information should NOT be sent to ETP or provided in any grant application without advance discussion with ETP and only with appropriate confidentiality agreements.
Scientific questions about appropriateness of an application should be directed to Roger J. Porter, MD, roger@epilepsytherapyproject.org.
Investigators must submit a Letter of Intent by March 1, 2012 by 11:59 pm ET.
The deadline for receipt of full Grant proposals is April 12, 2012 by 11:59 pm ET.
Full proposals will be accepted only from Investigators whose Letter of Intent was approved.
Epilepsy Foundation Targeted Research Initiative for Health Outcomes
Targeted Research Initiative for Health Outcomes
Application Deadline: March 21, 2012
Award Amount: up to $50,000 maximum for one year
Apply via Proposal Central website
The Targeted Research Initiative for Health Outcomes targets an important need for research to understand how different components of health care systems affect outcomes in people with epilepsy. The purpose of this initiative is to support research that generates initial data leading to more extensive projects that will generate knowledge that will ultimately improve the healthcare of persons with epilepsy. The broad focus of the proposal includes methodological aspects of health and outcome measurement, health care needs assessment, nature and determinants of disparities in healthcare, access to care, quality of life, comparative effectiveness research, insurance and healthcare system issues, and methods of health care delivery.
Applicants may request up to $50,000 maximum for one year.
Epilepsy Foundation 8301 Professional Place Landover, MD 20785-7223 Telephone: 1-800-332-1000 Fax: 1-301-577-2684 Email: ContactUs@efa.org
Targeted Research Initiative for Women with Epilepsy
Award Amount: up to $50,000 maximum for one year Apply via Proposal Central website
The Targeted Research Initiative for Women with Epilepsy grant program was developed to support research that generates initial data leading to more extensive projects that will have direct relevance to care of women with epilepsy. Research should focus on investigation of one of the many areas that preferentially affect women with epilepsy during the reproductive life cycle. The research may target any point along the reproductive spectrum, including puberty through menopause. Examples of topics of interest include, but are not limited to, the following areas: neuroendocrine disorders, hormone influence on seizure susceptibility, infertility, polycystic ovarian syndrome, contraceptive strategies, complications during pregnancy, and pregnancy outcomes.
The Foundation invites research grant applications from interested investigators to conduct innovative research in these areas, ultimately leading to advances in diagnosis and optimal therapeutic strategies for women with epilepsy. The broad focus of this RFP includes both fundamental and clinical research, and encourages translational research. The peer review for this program will assess proposals based not only on scientific merit, but also on relevance to the goals of the program.
Epilepsy Foundation Targeted Research Initiative for Youth
The Targeted Research Initiative for Youth grant program recognizes the increasing need for epilepsy and seizure research in populations from birth through the teen years involving pathophysiology, epidemiology, diagnosis, behavioral manifestations, medication therapy, and quality-of-life issues.
The Foundation invites research grant applications from investigators interested in psychosocial problems and comorbidities of infants, children and adolescents with epilepsy including, but not limited to topics such as psychiatric comorbidity; treatment of behavioral and cognitive comorbidities, including innovative techniques such as utilization of internet or computer based technologies; studies of the impact of impaired social cognition on educational and occupational outcomes; difficulties and treatment gaps for adolescents transitioning to adulthood; social supports for adolescents with epilepsy; health access and literacy including family communication with health care professionals; the impact of other health conditions (e.g. sleep difficulties, migraines, etc.) on epilepsy treatment and outcome.
Targeted Research Initiative for Severe Symptomatic Epilepsies
The Epilepsy Foundation is pleased to announce its first annual Targeted Research Initiative for Severe Symptomatic Epilepsies grant program. This program seeks to better understand, diagnose, identify co morbidities, and treat these rare but devastating epilepsy syndromes. The catastrophic epilepsies of childhood commonly include Othara's syndrome, severe myoclonic epilepsy in infancy (Dravet), infantile spasm, progressive myoclonic epilepsies, Lennox-Gastaut syndrome, Doose syndrome, Sturge-Weber syndrome, Rasmussen encephalitis and, in later childhood, Landau-Kleffner syndrome (LKS) and continuous spike and wave in slow-wave sleep (CSWSS).
Epilepsy Foundation Targeted Research Initiative for Morbidity and Mortality
The Targeted Research Initiative for Morbidity and Mortality supports research that generates initial data leading to more extensive projects that will generate knowledge that will ultimately improve the lives of persons with epilepsy. This initiative recognizes the need for research and new insights into these scientific areas.
The broad focus of the morbidity portion of this program includes: identification of somatic comorbidities in epilepsy that occur more than expected among controls, including but not limited to diabetes, gastrointestinal bleeding, chronic lung disease, congenital cardiac abnormalities, heart failure, and pneumonia; and associations between somatic comorbidities in epilepsy and epilepsy outcomes, including quality of life in epilepsy, seizure remission, stigma and other outcomes.
The mortality portion of the program is focused upon potentially preventable causes of death in epilepsy, such as accidents, suicide and SUDEP. Applicants are encouraged to examine risk factors for these causes of death in epilepsy; as well as interventions to decrease the presence of risk factors for these causes of death where risk factors have been identified.
Targeted Research Initiative for Cognitive and Psychiatric Aspects of Epilepsy
The Targeted Research Initiative for Cognitive and Psychiatric Aspects of Epilepsy supports research leading to new insights into the diagnosis etiology, complications and treatment of persons with epilepsy and mood disorders including comorbid cognitive disorders; depression, anxiety, suicidality, other psychiatric symptoms; and psychogenic non-epileptic seizures.
Epilepsy Foundation Health Sciences Student Fellowship
Award Amount: up to $3,000 Apply via Proposal Central website
The Health Sciences Student Fellowship stimulates individuals to pursue careers in epilepsy in either research or practice settings. Predoctoral training students in the Health Sciences may be accepted at any point in their schooling-following acceptance to the doctoral program, but before beginning the first year, or in the period immediately following their final year. ($3,000 stipend)
Epilepsy Foundation Behavioral Sciences Student Fellowship
Award Amount: up to $3,000
The Behavioral Sciences Student Fellowship stimulates individuals to pursue careers in epilepsy in either research or practice settings. Appropriate fields include sociology, social work, psychology, anthropology, nursing, economics, vocational rehabilitation, counseling, political science, and others relevant to epilepsy research or practice. Both graduate and undergraduate students are eligible. ($3,000 stipend)
12next
