Request for Applications for Records-Based Epidemiology Research
Autism Speaks
All Regions
09/08/2008
$375,000

Request for Applications for Records-Based Epidemiology Research

Only US territories and countries other than the United States are eligible to apply. Institutions located in the United States are NOT eligible to apply for this program, and no catchment area may be identified within the US.

The purpose of this RFA is to lay the groundwork for future epidemiological systems that would provide an estimate of the prevalence of the Autism Spectrum Disorders (ASDs) in regions outside of the United States. Autism Speaks requests pilot study proposals to develop a population-based, records-based surveillance system for identifying ASD from multiple sources in a defined geographic area outside of the United States. The method requires having a developed service, evaluation, and record-keeping infrastructure in the country (or territory) of interest. The developed method should include case definition(s), abstraction procedures and review of information for case determination that could be applied to the region of interest to estimate population prevalence, as well as potentially other sites. The feasibility study would provide information that would determine the region's capacity to design and implement population-based, multiple-source surveillance for ASDs and other DDs.

The deadline for applications is September 8, 2008.

Autism Speaks
2 Park Avenue
11th Floor
New York, NY 10016

Phone: (212) 252-8584
Fax: (212) 252-8676

Contact Us
contactus@autismspeaks.org

Epidemiologogist, Pediatrician, Physician Researcher, Public Health Expert
Restless Legs Syndrome Foundation Research Grant Program
Restless Legs Syndrome Foundation
All Regions
12/01/2008
$35,000

Restless Legs Syndrome Foundation Research Grant Program

Through its annual research program, the RLS Foundation honors promising scientists whose work addresses the goals of the Foundation. The RLS Foundation encourages grant applications for basic and clinical research studies of restless legs syndrome (RLS). Basic science leading to a better understanding of RLS, innovative approaches, interdisciplinary studies, and support of promising postdoctoral candidates is given funding priority.

The RLS Foundation encourages grant applications for basic and clinical research studies of restless legs syndrome (RLS). Areas in need of further research include, but are not limited to:

Epidemiology: Ascertain the prevalence and incidence of RLS, including:

Percentage of seriously affected individuals
Racial, gender, or geographic variations
Percentage of genetic versus other causes
Age of onset
Degree of association with comorbidities (such as ESRD, pregnancy, lumbosacral disease, Parkinson’s disease, and ADHD)
Neurophysiology

Identify neurophysiologic correlates in individuals with RLS and periodic limb movement disorder (PLMD), those with RLS and no PLMD, and those with PLMD and no RLS
Investigate the sensorimotor physiology associated with RLS symptoms
Dopamine: Investigate the dopaminergic regulation of movement and determine the receptors most associated with RLS

Genetics: Develop strategies for identifying the genes responsible for RLS

Iron: Examine the role of iron metabolism in RLS

Treatment models: Evaluate drug effects on RLS in vitro, using an animal model, or with advanced technology (i.e., MRI, PET scan)

Circadian rhythm: Identify, quantify, and correlate the role of circadian rhythms in RLS

Postdoctoral candidates: Support of the work of promising postdoctoral candidates or fellows working under the direction of established investigators on topics of potential relevance to RLS

Application Process: Initial contact should be through a letter of intent, containing the following: a one-page abstract of the proposed project, including its clearly stated relevance in addressing one or both of the RLS Foundation’s goals of finding a cure and developing effective treatments; a copy of the principal investigator’s NIH-style bio-bibliography; and a tentative budget as well as a list of other sources of funding.

Basic science leading to a better understanding of RLS, innovative approaches, interdisciplinary studies, and support of promising postdoctoral candidates will be given priority.

The Foundation will fund three to five grants of $20,000 to $35,000 each for one year with a potential for renewal of support for an additional year. The Foundation will not fund indirect costs. Payments will be made directly to the principal investigator’s institution.

The RLS Foundation
Contact us

LEGAL NAME: Restless Legs Syndrome Foundation, Inc

ADDRESS: 1610 14th St NW Suite 300 / Rochester, MN 55901

PHONE: 507-287-6465

INFO LINE: 877-INFO RLS

FAX: 507-287-6312

EMAIL: rlsfoundation@rls.org

WEBSITE: www.rls.org

TAX STATUS: 501 (c)(3)

Epidemiologogist, Sleep Specialist