Animal Testing Grants

NOVEL APPROACHES TO DRUG DISCOVERY FOR ALZHEIMER’S DISEASE
REQUEST FOR PROPOSALS
Scope of the Program
The objective of this Request for Proposals (RFP) from the biotechnology industry and academia is to catalyze and accelerate the discovery and development of innovative and effective treatments for Alzheimer’s disease. The program will fund high throughput screening of novel targets to identify hits and leads, lead validation and optimization through medicinal chemistry, and pre-clinical in-vitro and in-vivo evaluation, including pharmacology, toxicology, pharmacokinetics, formulation chemistry and the conduct of pre-clinical “proof of concept” studies.
A KEY FUNDING PRIORITY IS THE SUPPORT OF AD DRUG DISCOVERY IN EMERGING BIOTECH COMPANIES
The total number of grants awarded will be dependent upon the numbers, quality and costs of applications received. Proposals covering two years may be submitted, although the second year of funding will be contingent upon progress of the completed work, the investigator’s second-year work-plan, and the numbers and quality of competing proposals. Only one year of funding will be guaranteed. Former recipients of ADDF and ISOA funding are eligible to apply.
Funding Mechanism
If the award recipient is a biotechnology company, ADDF shall provide the grant funding in the form of a convertible note, an equity investment or a recoverable grant based on mutually agreed and negotiated terms.
If the award recipient is an academic institution, then ADDF shall provide funding in the form of an academic grant with terms that provide the Foundation with a return on its investment in the event of commercial success as a result of the research program funded by the Award as negotiated and mutually agreed.
Reporting Requirements
Scientific and financial progress reports are due every six months after the start of the award. A final report of research activities and expenditures is due at the termination of the funding period.
Eligibility Criteria
The proposed research may be conducted at a registered public or private biotechnology company or at any type of not-for-profit academic setting and the Principal Investigator must hold an MD or PhD degree.
Application Guidelines and Selection Criteria
All applications and supporting materials must be received by October 1, 2008. Applications will be reviewed by a Scientific Review Committee (SRC) and a final decision will be made by December 31, 2008.
The following criteria will be used to determine the merit of an application:
• Merit and feasibility of the proposed research and its relevance to drug discovery and development for treatment of Alzheimer’s disease.
• Qualifications of the scientific staff conducting the studies.
• Excellence of the research environment, including the availability of a multidisciplinary research team comprised of neuroscientists, medicinal chemists, pharmaceutical scientists, and the necessary animal models, facilities and equipment required for drug discovery and drug development. Research can be outsourced and consultants employed where appropriate and adequately justified.
• Likelihood that the project will lead to advancement in the treatment of Alzheimer’s disease.
Application Procedures
Application forms are available at www.AlzDiscovery.org.

Society of Toxicology Awards

In recognition of distinguished toxicologists and students, SOT presents several prestigious awards each year. In addition to receiving the specific award, recipients are honored at a special Awards Ceremony at the SOT Annual Meeting and their names are listed in SOT publications.

The deadline for most SOT 2009 Award nominations is October 9, 2008.

SOT Headquarters Office
1821 Michael Faraday Drive
Suite 300
Reston, Virginia 20190
Phone: (703) 438-3115
Fax: (703) 438-3113
Email: sothq@toxicology.org

Colgate-Palmolive Postdoctoral Fellowship Award in In Vitro Toxicology
Award Description The Colgate-Palmolive Company sponsors the Colgate-Palmolive Postdoctoral Fellowship Award in In Vitro Toxicology through the Society of Toxicology to advance the development of alternatives to animal testing in toxicological research. The award is given in alternate years and includes stipend and research-related costs (up to $38,500) for one year. The award may be extended for an additional year upon an agreement between Colgate-Palmolive and the postdoctoral fellow. Postdoctoral trainees in their first year of study beyond the Ph.D., M.D., or D.V.M. degree who are academic institutions, federal/national laboratories or research institutes worldwide may apply. The Awards Committee will review applications, which are due in even calendar years and the fellowship is awarded for the following year. The next award application deadline is October 9, 2008 for the 2009 award.

The award consists of a plaque and fellowship funds.

Criteria for award:

Postdoctoral trainees employed by academic institutions, federal/national laboratories, or research institutes
Doctoral degree must have been conferred before this fellowship is awarded
Preference will be given to applicants in their first year of postdoctoral study
Applicant or postdoctoral advisor must be a member or pending member of the Society. If the recipient is not a member, he or she will be required to submit a membership application before the fellowship is conferred
Proposed research should involve alternative methods as defined by the “three R’s”
Potential of the proposed work to contribute to the advancement of the field of alternatives
Items needed in the application:

Application form
Budget sheet
Description of research to be performed
Curriculum vitae
Reprints of up to three representative publications
Letter of reference from doctoral advisor
Letter of reference from the proposed postdoctoral advisor
Third letter of reference

Apply by downloading application files, completing, and mailing original plus 7 copies to:
Colgate-Palmolive Postdoctoral Fellowship Award in In Vitro Toxicology
Society of Toxicology
1821 Michael Faraday Drive, Suite 300
Reston, VA 20190

Letters of reference are mailed directly by the writer to the address above