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Research Experience for Undergraduates in Physiology and Neurobiology at the University of Connecticut
Submit complete application packet by March 14, 2014.
Funded by the National Science Foundation
Applications are now being accepted for the Summer 2014 program.
The NSF Research Experience for Undergraduates site in Physiology and Neurobiology at the University of Connecticut (Storrs, CT) offers paid summer research opportunities in the areas of renal and muscle physiology; developmental neurobiology, synaptic plasticity and neural circuits; and other areas in molecular and cell biology, microbiology and immunology. Interested students, especially underrepresented minorities, veterans, first-generation college students, and students with disabilities from institutions with limited research opportunities are encouraged to apply. Rising juniors and seniors are eligible (i.e., students who have completed their sophomore or junior year.) Our primary goal is to give students from primarily non-Ph.D. granting institutions opportunities to experience a stimulating research environment. Students can expect to acquire skills and knowledge to help them enter graduate research programs.
Participants will spend 10 weeks with UConn faculty and graduate students, participating in graduate level research projects on physiological systems in animals ranging from invertebrates and marine fish to birds and mammals. REU students will be part of a campus multidisciplinary REU community consisting of several programs in the physical sciences and engineering as well as physiology and neurobiology. The research program will be accompanied by seminars and a social program. Each student prepares a scientific poster of their research for presentation at an on campus REU symposium. The program lasts for 10 weeks, from Tuesday morning, May 27, through Friday August 1. Students must be available for the entire 10 week period.
All students receive a stipend, a meal allowance and housing (with other REU participants) in our modern, air-conditioned University Dormitories. Limited funds to assist with travel expenses to and from UConn are available if requested at the time of application. University recreational facilities will be available for participant use.
UConn is located midway between New York City (2.5 hours) and Boston (2 hours) in scenic eastern Connecticut.
REU Site PI:
Dr. Xinnian Chen
Dr. Larry Renfro
PNB REU Program
Physiology & Neurobiology, Unit 3156
University of Connecticut
Storrs, CT 06269-3156
FAX: (860) 486-3303
Scleroderma Foundation Research Grant Funding Program
The grant application deadline is 5 p.m. Eastern Sept. 15 each year. (Note: If the grant deadline falls on a weekend, the following Monday will be the deadline.)
Appropriate Areas of Research and Criteria
Appropriate research areas may include but are not limited to the following as they relate to scleroderma:
Studies of animal models.
Mechanisms of end organ damage.
Endothelial cell biology.
Models and markers of gender and genetic factors.
Stem cell biology.
Health services research (e.g. quality of life, health care delivery.)
Study of clinical manifestation.
Michael J. Fox Foundation for Parkinson's Research Target Validation Program
Fall 2014 Review Cycle
Informational Conference Call*: March 26, 2014 at 12pm US ET
Pre-proposals Due: May 28, 2014 – 6pm US ET
Full Proposal Invitations: June 18, 2014
Full Proposals Due (by invite only): August 6, 2014 – 6pm US ET
Anticipated Award Announcement: October 2014
Anticipated Funding: November 2014
*MJFF will hold a 45-minute conference call on the dates and times listed above to clarify and explain the goals of this funding initiative and answer applicant questions. To participate in the call and receive call-in details, please RSVP via email to email@example.com.
The Target Validation program supports work to determine whether manipulation of a defined biological target provides a disease-relevant beneficial outcome in a whole animal, mammalian model of PD. MJFF does not have any pre-conceived preferences for particular targets submitted to the Target Validation program. However, we recommend applicants consider the following:
The target should be clearly defined, such as:
A specific gene
A structural/functional feature of a protein (e.g., its enzymatic activity, protein conformation or ability to interact with other proteins)
Proposals seeking to manipulate global pathways without a clear target are not encouraged
Applicants may propose a variety of methods to manipulate a target, including but not limited to:
Use of pharmacological tools
Supporting data/explanation of the proposed pharmacological tool must be addressed in the body of the proposal.
Parameters that should be discussed include:
Selectivity for the target of interest
Pharmacokinetic/Pharmacodynamic measures that have been/will be assessed
Measures of target engagement
Use of biologic strategies such as:
Viral vector-mediated gene delivery, etc.
In Vivo Models
Applicants may also propose use of models appropriate for the target proposed including:
Previously established genetically engineered animal models including:
Knockout models where the target/gene of interest is deleted
Transgenic models whereby the target/gene of interest is over-expressed
Investigators should proposed to examine PD-relevant features or sensitivity to PD-associated factors during the course of their studies
Proposals may include intermediate tests using in vitro, ex vivo and/or model organisms (e.g., Drosophila, C. elegans) to optimize the ideal target manipulation strategy
These proposals must ultimately include within the grant funding period an evaluation of the target manipulation in a whole-animal mammalian model of PD
Note: The following types of proposals are not appropriate for the Target Validation program:
Proposals focused on new target identification and proposals testing cellular transplantation approaches.
Proposals seeking to generate new genetic (knockin, knockout, transgenic) models
Investigators seeking guidance to develop new models around their target are encouraged to contact firstname.lastname@example.org
Applicants seeking support for therapeutic development should submit to the Therapeutic Pipeline Program or contact MJFF research staff for guidance.
MJFF will commit up to $10 million to the Edmond J. Safra Core Programs for PD Research with the intention to support multiple awards. The Target Validation program supports two-year grants up to $250,000 total costs inclusive of both direct and indirect costs. The total annual direct costs cannot exceed $100,000. No more than 25% (Academic institutions) or 10% (for-profit organizations) of the direct costs may go to indirect costs.
Applications may be submitted by:
U.S. and non-U.S. biotechnology/pharmaceutical companies or other for-profit entities, either publicly or privately held,
U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.
Post-doctoral fellows are NOT eligible to apply as Principal Investigators to the Target Validation program.