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New Investigator Awards in Alzheimer's Disease
Funded by The Rosalinde and Arthur Gilbert Foundation and The Diane and Guilford Glazer Foundation, the major goal of this partnership program is to support important research in areas in which more scientific investigation is needed to improve the prevention, diagnosis, and treatment of Alzheimer's disease. The program also serves to encourage junior investigators in the United States and Israel to pursue research and academic careers in the neurosciences, and Alzheimer's disease in particular.
Projects in basic and translational research related to Alzheimer's disease (AD) that are clinically relevant, will be considered. Projects that focus on healthy brain aging are also considered. For one of the awards, priority may be given to an investigator with a research interest related to healthy brain aging. Areas of research could for example include learning and memory, nutrition, exercise, cardiovascular risk factors, as they relate to the brain and the aging process.
Examples of promising areas of research include, but are not limited to:
Basic mechanisms of aging in the central nervous system
Learning and memory
The Biology and Pathobiology of Synapses
Genetics of AD
Neuroimaging and precursors of AD
Cellular and Molecular pathways of AD
Biological Markers of AD
Exercise, nutrition and dietary factors
Neurogenesis and AD
Impact of environmental agents in CNS aging and early AD
Cardiovascular and cerebrovascular factors
It is anticipated that up to 4 grants of $100,000 each will be awarded in 2014. Applicants may propose to use the award over the course of one or two years as justified by the proposed research. Up to 8% of funds may be budgeted for overhead or indirect costs (not to exceed $7,407). Funding will begin July 1, 2014.
The applicant must be an independent investigator with independent research space as described in a form completed by the Dean or Department Chair, and must be no more than 10 years beyond start of postdoctoral research training as of July 1, 2014. Exceptions to the ten year rule may be requested for unusual circumstances by emailing an NIH-style biosketch to AFAR at email@example.com. The proposed research must be conducted at any type of not-for-profit setting in the United States or Israel.
The New Investigator Awards in Alzheimer's Disease do not provide support for:
Postdoctoral fellows in the laboratory of a senior investigator
Investigators who have already received major extramural funding (such as an R01 or NSF equivalent grant)
Senior faculty, i.e. at the rank of Associate Professor level or higher
NIH Intramural program employees
Applicants who are conducting research at a for-profit institution, or at an institution outside of the United States or Israel
Applicants cannot apply for the 2014 AFAR Research Grant Program or Glenn/AFAR BIG Program. Applications for this program will be considered for the AFAR Research Grant if deemed competitive.
Five criteria are used to determine the merit of an application:
Qualifications of the applicant;
Quality of the proposed research;
Relevance of the proposal to how mechanisms of aging may lead to AD or encourage healthy brain aging;
Excellence of the research environment;
Likelihood that the project will advance the applicant's career in basic research on the mechanisms of aging and AD or healthy brain aging
For one of the awards, priority may be given to an investigator with a research interest related to healthy brain aging provided the application is deemed to meet the highest standards set by AFAR's Research Committee.
The deadline for receipt of all Letters of Intent is December 16, 2013 at 5:00 p.m. EST. Please refer to the New Investigator LOI instructions. Incomplete LOIs cannot be considered. All applications and supporting materials must be submitted through the website www.afar.org/grants/. The Letters of Intent will be reviewed by a committee. Applicants will be notified by January 31, 2014, and a subset of applicants will be invited to submit a full application by March 17, 2014.
All LOI candidates who are invited to submit applications must have it endorsed by their institution. Final awards are announced by early June. The award start date is July 1, 2014. AFAR will not provide reviewer critiques to any applicants at any review level.
Investigators will be required to submit a brief narrative report on the progress of their research five months after the start date of the award. Final narrative and financial reports are required within three months following the end date of the award.
The award recipients are expected to attend the AFAR Grantee Conference which convenes AFAR grant recipients, mentors and leaders in the field to review and disseminate the research progress of the grantees and their findings. The meeting encourages networking, facilitates collaborations, and enhances the development of leadership. In addition, grant recipients of the New Investigator Awards in Alzheimer's are expected to attend a special session at the grantee conference.